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CAS 1802078-29-0

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Exendin-4 (1-8)

Description:
Exendin-4 (1-8) is a peptide derived from the saliva of the Gila monster, specifically a truncated form of the exendin-4 molecule, which is known for its role in glucose metabolism and appetite regulation. This peptide is characterized by its ability to mimic the action of glucagon-like peptide-1 (GLP-1), a hormone that enhances insulin secretion in response to meals and promotes satiety. Exendin-4 (1-8) exhibits high affinity for the GLP-1 receptor, making it a subject of interest in diabetes research and treatment. Its structure consists of a sequence of amino acids that contribute to its biological activity, stability, and receptor binding properties. The CAS number 1802078-29-0 uniquely identifies this specific peptide, facilitating its recognition in scientific literature and databases. Due to its therapeutic potential, particularly in managing type 2 diabetes, exendin-4 and its derivatives are being explored for their efficacy in improving glycemic control and reducing body weight in affected individuals.
Formula:C35H51N11O13
Synonyms:
  • Exendin-4 (1-8) trifluoroacetate salt H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-NH2 trifluoroacetate salt
  • HIS-GLY-GLU-GLY-THR-PHE-THR-SER-NH2
  • Exendin-4 (1-8)
  • H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-NH2
  • L-Serinamide, L-histidylglycyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-
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