CAS 1802078-31-4

Mca-SEVNLDAEFK(Dnp)

CAS: 1802078-31-4

Mca-SEVNLDAEFK(Dnp) is a peptide FRET substrate for Beta-secretase 1 (BACE-1), featuring the 'Swedish' Lys-Met/Asn-Leu mutation at the β-secretase cleavage site of the amyloid precursor protein (APP). Cleavage at the -Leu-Asp- site of Mca-SEVNLDAEFK(Dnp) releases the highly fluorescent 7-methoxycoumarin (Mca) fragment, which is freed from the quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher, leading to a significantly increased fluorescence intensity that is easily detectable.

Formula: C₆₈H₈₈N₁₄O₂₇

Color and Shape: Solid

Molecular weight: 1533.5

Ref: TM-T86868

Mca-(Asn670,Leu671)-Amyloid β/A4 Protein Precursor770 (667-675)-Lys(Dnp) ammonium acetate salt

CAS: 1802078-31-4

Please enquire for more information about Mca-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (667-675)-Lys(Dnp) ammonium acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₆₈H₈₈N₁₄O₂₇

Purity: Min. 95%

Molecular weight: 1,533.5 g/mol

Ref: 3D-FM110951

Mca-(Asn⁶⁷⁰,Leu⁶⁷¹)-Amyloid β/A4 Protein Precursor₇₇₀ (667-675)-Lys(Dnp)

CAS: 1802078-31-4

Fluorogenic (FRET) substrate for pro-memapsin-2 containing the β-secretase site of the Swedish mutation of APP, SEVNLDAEF.

Formula: C₆₈H₈₈N₁₄O₂₇

Purity: 98.0%

Color and Shape: Yellow Powder

Molecular weight: 1533.53

Ref: 01-4029476