CAS 180384-56-9

N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methyl-pyridine-2-sulfonamide

Description:

N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl]-5-methyl-pyridine-2-sulfonamide, with CAS number 180384-56-9, is a complex organic compound characterized by its multi-functional structure, which includes a pyrimidine core, a sulfonamide group, and various substituents that enhance its solubility and biological activity. This compound features a tetrazole moiety, which is known for its role in medicinal chemistry, particularly in the development of pharmaceuticals. The presence of hydroxyethoxy and methoxyphenoxy groups contributes to its potential as a bioactive agent, possibly influencing its interaction with biological targets. The sulfonamide group is often associated with antibacterial properties, although the specific biological activity of this compound would depend on its interactions at the molecular level. Overall, this substance is of interest in drug discovery and development, particularly in the context of targeting specific pathways or diseases, although detailed studies would be necessary to elucidate its full pharmacological profile.

Formula: C₂₅H₂₃N₉O₆S

InChI: InChI=1/C25H23N9O6S/c1-15-7-8-20(27-14-15)41(36,37)32-24-21(40-19-6-4-3-5-18(19)38-2)25(39-12-11-35)29-22(28-24)16-9-10-26-17(13-16)23-30-33-34-31-23/h3-10,13-14,35H,11-12H2,1-2H3,(H,28,29,32)(H,30,31,33,34)

SMILES: Cc1ccc(nc1)S(=O)(=O)Nc1c(c(nc(c2ccnc(c2)c2n[nH]nn2)n1)OCCO)Oc1ccccc1OC

Synonyms:

• Clazosentan [INN]
• Clazosentan
• Axv 034343
• Unii-3Drr0X4728
• N-{6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(2-(1H-tetrazol-5-yl)pyridin-4-yl)pyrimidin-4-yl}-5-methylpyridine-2-sulfonamide
• N-{6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)pyridin-4-yl]pyrimidin-4-yl}-5-methylpyridine-2-sulfonamide

2-Pyridinesulfonamide, N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-[2-(2H-tetrazol-5-yl)-4-pyridinyl]-4-pyrimidinyl]-5-methyl-

CAS: 180384-56-9

Formula: C₂₅H₂₃N₉O₆S

Purity: %

Color and Shape: Solid

Molecular weight: 577.5718

Ref: IN-DA0021Y5

Clazosentan

CAS: 180384-56-9

Clazosentan

Purity: ≥95%

Molecular weight: 577.57g/mol

Ref: 54-BUP09379

Clazosentan

Controlled Product

CAS: 180384-56-9

Formula: C₂₅H₂₃N₉O₆S

Color and Shape: Neat

Molecular weight: 577.572

Ref: TR-C565400

Clazosentan

CAS: 180384-56-9

Endothelin A (ETA) receptor antagonist

Formula: C₂₅H₂₃N₉O₆S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 577.57 g/mol

Ref: 3D-BC162764

Clazosentan

CAS: 180384-56-9

Clazosentan (Ro 61-1790) is a selective ET_A receptor antagonist that inhibits ET-1 vasoconstriction and prevents cerebral vasospasm.

Formula: C₂₅H₂₃N₉O₆S

Purity: 95.39% - >99.99%

Color and Shape: Solid

Molecular weight: 577.57

Ref: TM-T64084