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CAS 180414-93-1

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N-Fmoc-O-Phenyl-L-Tyrosine

Description:
N-Fmoc-O-Phenyl-L-Tyrosine is a derivative of the amino acid tyrosine, characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group on the nitrogen atom and a phenyl group attached to the hydroxyl group of the tyrosine side chain. This compound is commonly used in peptide synthesis as a building block due to its stability and ease of handling. The Fmoc group allows for selective protection of the amino group, facilitating the stepwise assembly of peptides while preventing unwanted reactions. N-Fmoc-O-Phenyl-L-Tyrosine is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its structure contributes to its role in enhancing the hydrophobicity of peptides, which can influence their biological activity and interactions. Additionally, the compound is utilized in various biochemical applications, including drug development and the study of protein interactions.
Formula:C30H25NO5
Synonyms:
  • N-Fmoc-O-Phenyl-L-Tyrosine
  • Fmoc-Tyr(Ph)-OH
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-phenoxyphenyl)propanoic acid
  • L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-phenyl-
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