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CAS 180414-94-2

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N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-methyl-L-norleucine

Description:
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-methyl-L-norleucine, commonly referred to as Fmoc-5-methyl-L-norleucine, is a synthetic amino acid derivative widely used in peptide synthesis and research. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is crucial for the selective protection of the amino group during peptide assembly. The presence of the 5-methyl group on the norleucine backbone enhances its hydrophobic characteristics, making it useful in the design of peptides with specific structural properties. The Fmoc group allows for easy removal under mild basic conditions, facilitating the stepwise synthesis of peptides. This compound is typically characterized by its stability, solubility in organic solvents, and its ability to participate in standard coupling reactions used in solid-phase peptide synthesis. Its unique structure contributes to the overall functionality and versatility in various biochemical applications, including drug development and the study of protein interactions.
Formula:C22H25NO4
InChI:InChI=1S/C22H25NO4/c1-14(2)11-12-20(21(24)25)23-22(26)27-13-19-17-9-5-3-7-15(17)16-8-4-6-10-18(16)19/h3-10,14,19-20H,11-13H2,1-2H3,(H,23,26)(H,24,25)/t20-/m0/s1
InChI key:InChIKey=UJOQOPBFLFQOJJ-FQEVSTJZSA-N
SMILES:C(OC(N[C@@H](CCC(C)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
Synonyms:
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-methylhexanoic acid
  • <span class="text-smallcaps">L</span>-Norleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-5-methyl-
  • Fmoc-Hle-Oh
  • Fmoc-Holeu-Oh
  • Fmoc-L-Hleu-Oh
  • Fmoc-L-Hol
  • Fmoc-L-Holeu-Oh
  • Fmoc-L-Homoleucine-Oh
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-L-Homoleucine
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-5-methyl-<span class="text-smallcaps">L</span>-norleucine
  • See more synonyms
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