CAS 180468-39-7

Solifenacin Hydrochloride

Description:

Solifenacin Hydrochloride is a medication primarily used to treat overactive bladder symptoms, such as frequent urination and urgency. It belongs to a class of drugs known as anticholinergics, which work by inhibiting the action of acetylcholine on muscarinic receptors in the bladder, thereby reducing involuntary contractions. The chemical formula for Solifenacin Hydrochloride is C23H26N2O3·HCl, and it has a molecular weight that reflects its complex structure. This compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a moderate to high lipophilicity. Its pharmacokinetics indicate a relatively long half-life, allowing for once-daily dosing. Common side effects may include dry mouth, constipation, and blurred vision, which are typical of anticholinergic medications. Due to its mechanism of action, Solifenacin Hydrochloride is contraindicated in patients with certain conditions, such as urinary retention or uncontrolled narrow-angle glaucoma. Overall, it is an effective option for managing symptoms of overactive bladder while requiring careful consideration of patient-specific factors.

Formula: C₂₃H₂₇ClN₂O₂

InChI: InChI=1/C23H26N2O2.ClH/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;/h1-9,18,21-22H,10-16H2;1H/t21-,22-;/m0./s1

SMILES: c1ccc(cc1)[C@H]1c2ccccc2CCN1C(=O)O[C@H]1CN2CCC1CC2.Cl

Synonyms:

• (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochlorid
• (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarboxylic Acid (3R)-1-Azabicyclo-[2.2.2]oct-3-yl Ester Hydrochloride
• (3R)-1-azabicyclo[2.2.2]oct-3-yl (1S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate hydrochloride (1:1)

(3R)-1-azabicyclo[2.2.2]octan-3-yl (1S)-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate hydrochloride

CAS: 180468-39-7

Formula: C₂₃H₂₇ClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 398.9257

Ref: IN-DA002203

(1S,3'R)-Solifenacin-d7 HCl(quinuclidinyl-d7)

CAS: 180468-39-7

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 405.97

Ref: 3U-D7570

Solifenacin hydrochloride

CAS: 180468-39-7

Solifenacin Hcl is a muscarinic receptor antagonist.

Formula: C₂₃H₂₇ClN₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 398.93

Ref: TM-T23379

Solifenacin Hydrochloride

Controlled Product

CAS: 180468-39-7

Formula: C₂₃H₂₆N₂O₂·ClH

Color and Shape: Neat

Molecular weight: 398.93

Ref: TR-S676700

Solifenacin-d7 Hydrochloride

Controlled Product

CAS: 180468-39-7

Applications Solifenacin-d7 hydrochloride is deuterium labelled Solifenacin hydrochloride (S676700), which is a Muscarinic M3 receptor antagoinst and used to treat urinary incontinence.
References Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002), Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004), Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004), Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005), Habb, F., et al.: Eur. Urol. 47, 376 (2005), Payne, C.K., et al.: Drugs, 66, 175 (2006),

Formula: C₂₃D₇H₁₉N₂O₂·ClH

Color and Shape: Neat

Molecular weight: 405.97

Ref: TR-S676704

Solifenacin hydrochloride

CAS: 180468-39-7

Muscarinic receptor antagonist

Formula: C₂₃H₂₇ClN₂O₂

Purity: Min. 95%

Molecular weight: 398.93 g/mol

Ref: 3D-FS27853