Description:2,6-Difluorobenzoyl chloride is an aromatic acyl chloride characterized by the presence of two fluorine atoms located at the 2 and 6 positions of the benzene ring, along with a carbonyl chloride functional group. This compound is typically a colorless to pale yellow liquid with a pungent odor, indicative of its reactivity. It is known for its role as an acylating agent in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. The presence of fluorine atoms enhances its electrophilic character, making it a useful intermediate in the synthesis of fluorinated compounds. 2,6-Difluorobenzoyl chloride is sensitive to moisture and can hydrolyze to form the corresponding carboxylic acid, thus it should be handled under anhydrous conditions. Safety precautions are essential when working with this compound, as it can cause severe irritation to the skin, eyes, and respiratory system. Proper storage in a cool, dry place away from incompatible materials is recommended to maintain its stability and reactivity.
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