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CAS 180694-97-7

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Mimopezil

Description:
Mimopezil is a chemical compound primarily recognized for its role as a selective inhibitor of the enzyme acetylcholinesterase, which is involved in the breakdown of the neurotransmitter acetylcholine. This inhibition can enhance cholinergic neurotransmission, making it of interest in the treatment of cognitive disorders, particularly Alzheimer's disease. Mimopezil is characterized by its ability to cross the blood-brain barrier, which is crucial for its therapeutic effects on central nervous system functions. The compound has a specific molecular structure that contributes to its pharmacological properties, including its affinity for the target enzyme and its overall bioavailability. Additionally, Mimopezil has been studied for its potential neuroprotective effects, which may further support cognitive function. As with many pharmacological agents, its safety profile, side effects, and interactions with other medications are important considerations in its clinical use. Overall, Mimopezil represents a significant area of research in neuropharmacology, particularly in the context of age-related cognitive decline.
Formula:C23H23ClN2O3
InChI:InChI=1/C23H23ClN2O3/c1-4-17-14-7-13(2)11-23(17,18-5-6-21(27)26-19(18)9-14)25-12-15-8-16(24)10-20(29-3)22(15)28/h4-8,10,12,14,28H,9,11H2,1-3H3,(H,26,27)/b17-4+,25-12+/t14-,23+/m0/s1
Synonyms:
  • Xipulin
  • ZT-1
  • ZT 1
  • ZT 1
  • Mimopezil [INN]
  • 5,9-Methanocycloocta[b]pyridin-2(1H)-one, 5-[[(5-chloro-2-hydroxy-3-methoxyphenyl)methylene]amino]-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, [5R-(5α,9β,11E)]-
  • 5,9-Methanocycloocta(b)pyridin-2(1H)-one, 5-(((5-chloro-2-hydroxy-3- methoxyphenyl)methylene)amino)-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (5R-(5alpha,9beta,11E))-
  • 5,9-Methanocycloocta[b]pyridin-2(1H)-one, 5-[[(5-chloro-2-hydroxy-3-methoxyphenyl)methylene]amino]-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-, (5R,9R,11E)-
  • N-(2-Hydroxy-3-methoxy-5-chlorobenzylidene)huperzine A
  • (5R,9R,11E)-5-[[(5-Chloro-2-hydroxy-3-methoxyphenyl)methylene]amino]-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2(1H)-one
  • See more synonyms
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