CAS 1807988-47-1

IITZ-01

CAS: 1807988-47-1

Formula: C₂₆H₂₃FN₈O

Purity: 98%

Molecular weight: 482.5122

Ref: IN-DA01EOAL

IITZ-01

CAS: 1807988-47-1

IITZ-01

Purity: ≥98%

Molecular weight: 482.51g/mol

Ref: 54-BUP10472

IITZ-01

CAS: 1807988-47-1

IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)

Formula: C₂₆H₂₃FN₈O

Purity: 99.31%

Color and Shape: Solid

Molecular weight: 482.51

Ref: TM-T6799

IITZ-01

CAS: 1807988-47-1

IITZ-01 is a small molecule that induces autophagy by targeting the mitochondrial membrane potential and inhibiting the ubiquitin-proteasome pathway. It has been shown to have anticancer activity against cancer cells in vitro and in vivo. IITZ-01 has been shown to be effective against breast, prostate, pancreatic, colon, liver and lung cancers. The treatment of IITZ-01 sensitizes carcinoma cells to chemotherapeutic agents such as cisplatin or doxorubicin. IITZ-01 also induces autophagosome formation, which may be due to its ability to stabilize mitochondria by preventing the dissipation of mitochondrial membrane potential.

Formula: C₂₆H₂₃FN₈O

Purity: Min. 95%

Molecular weight: 482.51 g/mol

Ref: 3D-HXC98847