CAS 1808011-22-4
:EPZ031686
Description:
EPZ031686, with the CAS number 1808011-22-4, is a small molecule that functions primarily as a selective inhibitor of the enzyme EZH2 (enhancer of zeste homolog 2). This compound is notable for its potential therapeutic applications in the treatment of various cancers, particularly those characterized by mutations or dysregulation of the EZH2 gene. The inhibition of EZH2 can lead to the reactivation of tumor suppressor genes and a subsequent reduction in cancer cell proliferation. EPZ031686 is typically characterized by its specific binding affinity to the target enzyme, which is crucial for its efficacy. Additionally, it may exhibit favorable pharmacokinetic properties, including oral bioavailability and a manageable safety profile, making it a candidate for further clinical development. As with many investigational compounds, ongoing research is essential to fully elucidate its mechanism of action, therapeutic potential, and any associated side effects.
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Found 3 products.
EPZ031686
CAS:<p>EPZ031686 is a small molecule that binds to methyltransferases and inhibits the transfer of methyl groups from S-adenosylmethionine (SAM) to histones. This leads to decreased levels of lysine methylation, which has been shown to affect cancer cell viability and prognosis. EPZ031686 has been shown to induce autophagy in bladder cancer cells, and this may be due to its ability to inhibit growth factor signaling. EPZ031686 also reduces the expression of genes involved in epithelial-mesenchymal transition, which may have clinical relevance for the treatment of cancers such as bladder cancer.</p>Formula:C26H34ClF3N4O4SPurity:Min. 95%Molecular weight:591.09 g/molEPZ031686
CAS:<p>EPZ031686 is an effective inhibitor of SMYD3 inhibitor with an IC50 of 3 nM and can be used in studies about cancer.</p>Formula:C26H34ClF3N4O4SPurity:99.67%Color and Shape:SolidMolecular weight:591.09
