CAS 1809053-38-0
:Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 1 products.
Histone acetyltransferase GCN5
CAS:<p>Histone acetyltransferase GCN5 is a histone acetyltransferase that has been shown to be involved in the regulation of transcriptional activation. This enzyme acetylates histones H3 and H4 at physiological levels, and is found in human cells. Histone acetylation by GCN5 may affect transcriptional activation by altering chromatin structure and creating regions of open DNA that allow access to the transcription machinery. The expression of this enzyme has been shown to be regulated by growth factors such as β1-integrin and TGF-β1. Increased expression of GCN5 in cancer cells may lead to increased tumor growth rates, which could be due to its ability to promote histone h3 acetylation in xenograft mouse tumor models.</p>Purity:Min. 95%
