CAS 1810742-60-9

4(1H)-Quinazolinone, 7-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-2,3-dihydro-2,2-dimethyl-1-[(1R)-1-phenylethyl]-

Description:

4(1H)-Quinazolinone, 7-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-2,3-dihydro-2,2-dimethyl-1-[(1R)-1-phenylethyl]- is a complex organic compound characterized by its multi-cyclic structure, which includes a quinazolinone core and an imidazopyridine moiety. This compound typically exhibits properties such as moderate solubility in organic solvents and potential bioactivity, making it of interest in medicinal chemistry. The presence of multiple functional groups suggests that it may engage in various chemical interactions, potentially influencing its pharmacological profile. Its stereochemistry, indicated by the (1R)-1-phenylethyl group, may also play a crucial role in its biological activity and receptor interactions. As a synthetic compound, it may be explored for applications in drug development, particularly in targeting specific biological pathways. However, detailed studies on its toxicity, efficacy, and mechanism of action would be necessary to fully understand its potential applications in pharmaceuticals.

Formula: C₂₄H₂₃N₅O₂

Synonyms:

• 4(1H)-Quinazolinone, 7-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-2,3-dihydro-2,2-dimethyl-1-[(1R)-1-phenylethyl]-

PKCTheta-IN-2

CAS: 1810742-60-9

PKCTheta-IN-2 (compound 14) is a potent and selective inhibitor of PKCθ, with an IC50 value of 0.25 nM. It demonstrates good selectivity across a broad range of kinases, including the PKC subfamily (30 kinases). Additionally, PKCTheta-IN-2 effectively inhibits the production of IL-2 in mice, where it exhibits an IC50 of 682 nM.

Formula: C₂₄H₂₃N₅O₂

Color and Shape: Solid

Molecular weight: 413.47

Ref: TM-T201189