CAS 1811-31-0

GalNAc

Description:

GalNAc, or N-acetylgalactosamine, is an amino sugar and a derivative of galactose. It is characterized by the presence of an acetyl group attached to the amino group on the galactose molecule. This compound plays a crucial role in various biological processes, particularly in the synthesis of glycoproteins and glycolipids, where it serves as a building block for complex carbohydrates. GalNAc is also involved in cell signaling and recognition processes, influencing cellular interactions and immune responses. It is typically found in the form of a white crystalline powder and is soluble in water. The compound is non-toxic and is used in various biochemical applications, including research and therapeutic development. Its structural properties allow it to participate in various enzymatic reactions, making it significant in the study of glycobiology. Overall, GalNAc is an essential component in the biochemistry of living organisms, contributing to the complexity and functionality of cellular structures.

Formula: C₈H₁₅NO₆

InChI: InChI=1S/C8H15NO6/c1-4(12)9-5(2-10)7(14)8(15)6(13)3-11/h2,5-8,11,13-15H,3H2,1H3,(H,9,12)/t5-,6+,7+,8-/m0/s1

InChI key: InChIKey=MBLBDJOUHNCFQT-OSMVPFSASA-N

SMILES: [C@H]([C@H]([C@H]([C@@H](CO)O)O)O)(NC(C)=O)C=O

Synonyms:

• 2-(Acetylamino)-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• 2-(Acetylamino)-2-deoxy-D-galactose
• 2-Acetamido-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• 2-Acetamido-2-deoxy-D-galactose
• 2-Deoxy-2-acetamido-<span class="text-smallcaps">D</span>-galactose
• 2-Deoxy-2-acetamido-D-galactose
• 2-N-Acetyl-<span class="text-smallcaps">D</span>-galactosamine
• 2-N-Acetyl-D-galactosamine
• <span class="text-smallcaps">D</span>-Galactose, 2-(acetylamino)-2-deoxy-
• <span class="text-smallcaps">D</span>-N-Acetylgalactosamine
• D-N-Acetylgalactosamine
• GalNAc
• Galactosamine, N-acetyl-, <span class="text-smallcaps">D</span>-
• Galactosamine, N-acetyl-, D-
• Galactose, 2-acetamido-2-deoxy-, <span class="text-smallcaps">D</span>-
• Galactose, 2-acetamido-2-deoxy-, D-
• N-Acetyl-2-amino-2-deoxy-<span class="text-smallcaps">D</span>-galactose
• N-Acetyl-2-amino-2-deoxy-D-galactose
• N-Acetyl-2-amino-2-deoxygalactose
• N-Acetyl-<span class="text-smallcaps">D</span>-galactosamine
• N-Acetyl-D-galactosamine
• N-Acetyl-β-D-galaktosamin
• N-Acetylchondrosamine
• N-Acetylgalactosamine
• N-acetil-β-D-galactosamina
• N-acetyl-β-D-galactosamine

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine is the initial O-linked sugar to many serine and threonine residues in protein glycosylation. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The o

Formula: C₈H₁₅NO₆

Color and Shape: Crystals or crystalline powder, White

Molecular weight: 221.21

Ref: 02-J66095

D-Galactose, 2-(acetylamino)-2-deoxy-

CAS: 1811-31-0

Formula: C₈H₁₅NO₆

Purity: 80%

Color and Shape: Solid

Molecular weight: 221.2078

Ref: IN-DA0022OP

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine

Formula: C₈H₁₅NO₆

Purity: 95%

Color and Shape: white solid

Molecular weight: 221.21g/mol

Ref: 54-OR7700T

D-N-Acetylgalactosamine

CAS: 1811-31-0

D-N-Acetylgalactosamine

Purity: ≥98%

Molecular weight: 221.21g/mol

Ref: 54-BUP18207

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine

Formula: C₈H₁₅NO₆

Purity: 97%

Color and Shape: white to off-white solid

Molecular weight: 221.21g/mol

Ref: 54-BIM1065

D-N-Acetylgalactosamine

CAS: 1811-31-0

D-N-Acetylgalactosamine (N-Acetyl-D-galactosamine) is an important constituent of brain heteropolysaccharides (glycoproteins).

Formula: C₈H₁₅NO₆

Purity: 99.79% - 99.91%

Color and Shape: White Crystalline Powder

Molecular weight: 221.21

Ref: TM-T4708

N-Acetyl-D-galactosamine

Controlled Product

CAS: 1811-31-0

Applications N-Acetyl-D-galactosamine (cas# 1811-31-0) is a compound useful in organic synthesis.
References Nakajima, M., et al.: App. Microbiol. Biotechnol., 83, 109 (2009), Singh, S., et al.: Mol. Immunol., 46, 1240 (2009),

Formula: C₈H₁₅NO₆

Color and Shape: Neat

Molecular weight: 221.2078

Ref: TR-A177000

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-Acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of acetylgalactosamine residues attached to the IgA O-linked glycans of Crohn'sdisease patients is significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohn's disease (Inoue, 2012).

Formula: C₈H₁₅NO₆

Purity: Min. 98%

Color and Shape: White Powder

Molecular weight: 221.21 g/mol

Ref: 3D-MA04390

N-Acetyl-D-galactosamine

CAS: 1811-31-0

N-acetyl D-galactosamine (GalNAc) is an aldohexose (2-acetamido-2-deoxygalactose) in which the hydroxyl group at position 2 is replaced by a N-acetyl group (Collins, 2006). GalNAc forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides. The number of GalNAc residues attached to the IgA O-linked glycans of Crohns Disease patients was significantly decreased, and strongly correlated with clinical activity. It is suggested that alterations of GalNAc attachment in IgA may be useful as a novel diagnostic and prognostic marker of Crohns Disease (Inoue, 2012).

Formula: C₈H₁₅NO₆

Purity: Min. 99.0 Area-%

Molecular weight: 221.21 g/mol

Ref: 3D-A-1170

N-((2R,3R,4R,5R)-3,4,5,6-Tetrahydroxy-1-oxohexan-2-yl)acetamide

CAS: 1811-31-0

Formula: C₈H₁₅NO₆

Purity: 80%

Color and Shape: Solid, Crystalline or Powder

Molecular weight: 221.209

Ref: 10-F239286

N-Acetyl-D-galactosamine, plant-based

CAS: 1811-31-0

N-Acetyl-D-galactosamine (GalNAc) is an aldohexose. It forms a key part of both N- and O-linked glycoproteins, glycolipids, gangliosides, blood groups, glycosaminoglycans (chondroitin and dermatan sulfate) and human milk oligosaccharides.This N-Acetyl-D-galactosamine product (MA184543) is plant-based and produced synthetically from Arabic gum.GalNAc clusters and derivatives, typically composed of three (or more) GalNAc moieties arranged in a specific spatial configuration, are a powerful tool for targeted delivery of nucleic acid therapeutics, specifically in liver targeted therapies. These multivalent ligands effectively bind and internalize via the asialoglycoprotein receptor (ASGPR) expressed on the surface of hepatocytes.

Formula: C₈H₁₅NO₆

Purity: Min. 97 Area-%

Molecular weight: 221.21 g/mol

Ref: 3D-MA184543