CAS 181114-32-9

Quinazoline, 2-phenyl-4-[4-(phenylmethyl)-1-piperazinyl]-

Description:

Quinazoline, 2-phenyl-4-[4-(phenylmethyl)-1-piperazinyl]- is a chemical compound characterized by its quinazoline core structure, which consists of a fused benzene and pyrimidine ring. This compound features a phenyl group at the 2-position and a piperazine moiety substituted at the 4-position, specifically with a phenylmethyl group. The presence of the piperazine ring contributes to its potential biological activity, as piperazine derivatives are often associated with various pharmacological effects, including anxiolytic and antidepressant properties. The compound's molecular structure suggests it may interact with neurotransmitter systems, making it of interest in medicinal chemistry. Additionally, its CAS number, 181114-32-9, allows for precise identification in chemical databases. The compound's solubility, stability, and reactivity would depend on its specific functional groups and overall molecular configuration, which can influence its behavior in biological systems and its potential applications in drug development.

Formula: C₂₅H₂₄N₄

Synonyms:

• Quinazoline, 2-phenyl-4-[4-(phenylmethyl)-1-piperazinyl]-
• AChE/Aβ-IN-5

AChE/Aβ-IN-5

CAS: 181114-32-9

Compound AV-2, also known as AChE/Aβ-IN-5, is a bifunctional inhibitor that acts on AChE and auto-induced Aβ (Amyloid-β) aggregation. This compound has demonstrated significant efficacy in mitigating cognitive impairment in mice induced by scopolamine and Aβ [1].

Formula: C₂₅H₂₄N₄

Color and Shape: Solid

Molecular weight: 380.48

Ref: TM-T85551