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CAS 181311-44-4

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FMOC-TRP(BOC)-OPFP

Description:
FMOC-TRP(BOC)-OPFP, with the CAS number 181311-44-4, is a chemical compound commonly used in peptide synthesis and research. It is a protected derivative of tryptophan, featuring a 9-fluorenylmethoxycarbonyl (FMOC) group and a tert-butyloxycarbonyl (BOC) group, which serve to protect the amino and carboxyl functionalities during synthetic procedures. The presence of the OPFP (o-nitrophenyl) group enhances its reactivity, making it suitable for coupling reactions in solid-phase peptide synthesis. This compound is typically characterized by its stability under standard laboratory conditions, while the protective groups can be selectively removed under specific conditions to yield the free amino acid or peptide. Its solubility is generally good in organic solvents, which facilitates its use in various synthetic protocols. Overall, FMOC-TRP(BOC)-OPFP is a valuable intermediate in the synthesis of peptides, particularly those containing tryptophan, and is utilized in both academic and pharmaceutical research settings.
Formula:C37H29F5N2O6
Synonyms:
  • N-Alpha-(9-Fluorenylmethyloxycarbonyl)-N-In-T-Butyloxycarbonyl-L-Tryptophan Pentafluorphenyl Ester
  • N-Alpha-Fmoc-N-In-T-Boc-L-Tryptophan Pentafluorophenyl Ester
  • Fmoc-L-Trp(Boc)-Opfp
  • Fmoc-N-In-Boc-L-Tryptophan Pentafluorophenyl Ester
  • L-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 2,3,4,5,6-pentafluorophenyl ester
  • 1-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tryptophan pentafluorophenyl ester
  • FMOC-TRP(BOC)-OPFP
  • (S)-tert-Butyl 3-(2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-oxo-3-(perfluorophenoxy)propyl)-1H-indole-1-carboxylate
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