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CAS 181365-26-4

:

1-(TERT-BUTOXYCARBONYL)INDOLE-3-BORONIC ACID

Description:
1-(Tert-Butoxycarbonyl)indole-3-boronic acid is an organoboron compound characterized by the presence of both a boronic acid functional group and a tert-butoxycarbonyl (Boc) protecting group attached to an indole structure. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but may have limited solubility in water due to the hydrophobic nature of the indole ring. The boronic acid moiety is known for its ability to form reversible covalent bonds with diols, making it useful in various applications, including Suzuki-Miyaura cross-coupling reactions in organic synthesis. The Boc group serves as a protective group for amines, facilitating the selective functionalization of the indole nitrogen. This compound is often utilized in medicinal chemistry and materials science for the development of biologically active molecules and polymers. Its stability and reactivity can be influenced by factors such as pH and the presence of other functional groups in a reaction environment.
Formula:C13H16BNO4
Synonyms:
  • Indole-1-Carboxylic Acid T-Butyl Ester-3-Boronic Acid
  • Akos Brn-0395
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