CAS 1816331-66-4

GSK864

CAS: 1816331-66-4

GSK864

Purity: ≥95%

Molecular weight: 558.6g/mol

Ref: 54-BUP04436

GSK864

CAS: 1816331-66-4

GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).

Formula: C₃₀H₃₁FN₆O₄

Purity: 97.07%

Color and Shape: Solid

Molecular weight: 558.6

Ref: TM-T15442

GSK864

CAS: 1816331-66-4

GSK864 is a small molecule that inhibits pd-l1, a protein that is important for the development of cancer. GSK864 has been shown to inhibit the production of histone H3, which is an essential component of the nucleosome and plays a role in DNA replication and transcription. GSK864 also promotes demethylation and inhibits 2-hydroxyglutarate (HG), which is involved in cellular metabolism and produces energy. This drug also increases production of secretome, which contains proteins that are involved in tumor growth.

Formula: C₃₀H₃₁FN₆O₄

Purity: Min. 95%

Molecular weight: 558.6 g/mol

Ref: 3D-RXC33166