CAS 1816331-66-4

Formula: C30H31FN6O4

InChI: InChI=1S/C30H31FN6O4/c1-17-12-21(13-18(2)25(17)41-4)34-27(38)24-22-15-36(28(39)23-6-5-11-33-23)16-30(3,29(32)40)26(22)37(35-24)14-19-7-9-20(31)10-8-19/h5-13,33H,14-16H2,1-4H3,(H2,32,40)(H,34,38)/t30-/m0/s1

InChI key: DUCNNEYLFOQFSW-PMERELPUSA-N

SMILES: CC1=CC(=CC(=C1OC)C)NC(=O)C2=NN(C3=C2CN(C[C@]3(C)C(=O)N)C(=O)C4=CC=CN4)CC5=CC=C(C=C5)F

(S)-1-(4-Fluorobenzyl)-N3-(4-methoxy-3,5-dimethylphenyl)-7-methyl-5-(1H-pyrrole-2-carbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3,7-dicarboxamide

CAS: 1816331-66-4

Purity: 97%

Ref: IN-DA01EOEJ

GSK864

CAS: 1816331-66-4

GSK864

Formula: C₃₀H₃₁FN₆O₄

Purity: ≥95%

Molecular weight: 558.6

Ref: 54-BUP04436

GSK864

CAS: 1816331-66-4

(S)-1-(4-Fluorobenzyl)-N3-(4-methoxy-3,5-dimethylphenyl)-7-methyl-5-(1H-pyrrole-2-carbonyl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3,7-dicarboxamide

Formula: C₃₀H₃₁FN₆O₄

Purity: 97%

Molecular weight: 558.6

Ref: IN-DG627511

GSK864

CAS: 1816331-66-4

GSK864 is a small molecule that inhibits pd-l1, a protein that is important for the development of cancer. GSK864 has been shown to inhibit the production of histone H3, which is an essential component of the nucleosome and plays a role in DNA replication and transcription. GSK864 also promotes demethylation and inhibits 2-hydroxyglutarate (HG), which is involved in cellular metabolism and produces energy. This drug also increases production of secretome, which contains proteins that are involved in tumor growth.

Formula: C₃₀H₃₁FN₆O₄

Purity: Min. 95%

Molecular weight: 558.6 g/mol

Ref: 3D-RXC33166

GSK864

CAS: 1816331-66-4

GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).

Formula: C₃₀H₃₁FN₆O₄

Purity: 97.07%

Color and Shape: White Solid

Molecular weight: 558.6

Ref: TM-T15442