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CAS 181705-93-1

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4-FLUOROPHENYLZINC BROMIDE

Description:
4-Fluorophenylzinc bromide is an organozinc compound characterized by the presence of a fluorinated phenyl group bonded to a zinc atom, along with a bromide ion. This compound typically appears as a colorless to pale yellow solid and is known for its reactivity in organic synthesis, particularly in cross-coupling reactions such as the Suzuki-Miyaura reaction. The fluorine atom in the phenyl group can influence the electronic properties of the compound, enhancing its reactivity and selectivity in various chemical transformations. 4-Fluorophenylzinc bromide is often utilized as a nucleophile in the formation of carbon-carbon bonds, making it valuable in the synthesis of pharmaceuticals and agrochemicals. It is important to handle this compound with care, as organozinc reagents can be pyrophoric and sensitive to moisture, requiring an inert atmosphere for storage and use. Proper safety protocols should be followed to mitigate risks associated with its handling.
Formula:C6H4BrFZn
InChI:InChI=1/C6H4F.BrH.Zn/c7-6-4-2-1-3-5-6;;/h2-5H;1H;/q-1;;+2/p-1/rC6H4F.BrZn/c7-6-4-2-1-3-5-6;1-2/h2-5H;/q-1;+1
SMILES:C1=CC=C([CH-]C=1)F.Br.[Zn]
Synonyms:
  • 4-Fluorophenylzinc Bromide, 0.5M Solutio N In Tetrahydrofuran
  • 4-Fluorophenylzinc Bromide Solution
  • Bromozinc(1+) Fluorobenzenide
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