CAS 1817735-37-7

1,1,1-Trifluoroethyl-PEG5-Propargyl

Description:

1,1,1-Trifluoroethyl-PEG5-Propargyl is a specialized chemical compound that combines a trifluoroethyl group with a polyethylene glycol (PEG) moiety and a propargyl functional group. The trifluoroethyl group imparts unique properties such as increased lipophilicity and stability, making it useful in various applications, including pharmaceuticals and materials science. The PEG segment, consisting of five ethylene glycol units, enhances solubility in aqueous environments and biocompatibility, which is particularly advantageous in drug delivery systems. The propargyl group allows for further chemical modifications through click chemistry, facilitating the conjugation of other molecules or biomolecules. This compound is often utilized in research and development for creating functionalized polymers, drug formulations, and bioconjugates. Its unique combination of hydrophilic and hydrophobic characteristics, along with the ability to participate in selective reactions, makes it a valuable tool in synthetic organic chemistry and materials engineering. As with all chemical substances, proper handling and safety protocols should be observed due to potential hazards associated with its components.

Formula: C₁₃H₂₁F₃O₅

Synonyms:

• 1,1,1-Trifluoroethyl-PEG4-propargyl
• 1,1,1-Trifluoroethyl-PEG5-Propargyl

1,1,1-Trifluoroethyl-PEG4-propargyl

CAS: 1817735-37-7

1,1,1-Trifluoroethyl-PEG4-propargyl is a polyethylene glycol (PEG)-based PROTAC linker employed for the synthesis of PROTACs [1].

Formula: C₁₃H₂₁F₃O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 314.3

Ref: TM-T17318

1,1,1-Trifluoroethyl-PEG5-propargyl

CAS: 1817735-37-7

1,1,1-Trifluoroethyl-PEG5-propargyl is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. 1,1,1-Trifluoroethyl-PEG5-propargyl is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₁₃H₂₁F₃O₅

Purity: Min. 95%

Molecular weight: 314.3 g/mol

Ref: 3D-SXC73537