Carboxy-PEG2-sulfonic acid, identified by its CAS number 1817735-45-7, is a synthetic polymer that combines polyethylene glycol (PEG) with carboxylic acid and sulfonic acid functional groups. This compound typically exhibits high solubility in water due to the hydrophilic nature of the PEG backbone, which enhances its compatibility with biological systems. The presence of carboxylic and sulfonic acid groups imparts acidic properties, allowing for potential applications in drug delivery, bioconjugation, and as a stabilizing agent in various formulations. The sulfonic acid group can also enhance the compound's ionic character, which may influence its interactions with other molecules, including proteins and nucleic acids. Additionally, the polymer's structure can be tailored to modify its molecular weight and functionalization, making it versatile for various biomedical and industrial applications. Overall, Carboxy-PEG2-sulfonic acid is characterized by its hydrophilicity, functional versatility, and potential for use in advanced materials and therapeutic contexts.

Carboxy-PEG2-sulfonic acid is a PEG linker containing a carboxylic acid and sulfonic acid end group. The terminal carboxylic acid can participate in reactions with primary amines in the presence of activators such as EDC and HATU. Sulfonic acid can undergo esterification, halogenation and replacement reactions. The hydrophilic PEG linker increases the compound's water solubility in aqueous media.

Carboxy-PEG2-sulfonic acid

1817735-45-7: Carboxy-PEG2-sulfonic acid, identified by its CAS number 1817735-45-7, is a synthetic polymer that combines polyethylene glycol (PEG) with carboxylic acid and sulfonic acid functional groups. This compound typically exhibits high solubility in water due to the hydrophilic nature of the PEG backbone, which enhances its compatibility with biological systems. The presence of carboxylic and sulfonic acid groups imparts acidic properties, allowing for potential applications in drug delivery, bioconjugation, and as a stabilizing agent in various formulations. The sulfonic acid group can also enhance the compound's ionic character, which may influence its interactions with other molecules, including proteins and nucleic acids. Additionally, the polymer's structure can be tailored to modify its molecular weight and functionalization, making it versatile for various biomedical and industrial applications. Overall, Carboxy-PEG2-sulfonic acid is characterized by its hydrophilicity, functional versatility, and potential for use in advanced materials and therapeutic contexts.

<p>Carboxy-PEG2-sulfonic acid is a polyethylene glycol (PEG)-derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1</p>

<p>Carboxy-PEG2-sulfonic acid is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Carboxy-PEG2-sulfonic acid is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

CAS 1817735-45-7

Carboxy-PEG2-sulfonic acid

Carboxy-PEG2-sulfonic acid

Ref: TM-T14866

Carboxy-PEG2-sulfonic acid

Ref: 3D-SXC73545