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CAS 181785-84-2

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Elvucitabine

Description:
Elvucitabine, with the CAS number 181785-84-2, is a synthetic nucleoside analog that belongs to the class of antiviral medications, specifically designed for the treatment of HIV infection. It is a derivative of cytidine and functions as a reverse transcriptase inhibitor, which is crucial in blocking the replication of the virus within the host cells. Elvucitabine exhibits a favorable pharmacokinetic profile, including good oral bioavailability and a relatively long half-life, which supports its potential for once-daily dosing. The compound has demonstrated activity against various strains of HIV, including those resistant to other nucleoside reverse transcriptase inhibitors. Its mechanism of action involves incorporation into the viral DNA during replication, leading to chain termination. While it has shown promise in clinical studies, further research is necessary to fully establish its efficacy and safety profile in diverse patient populations. As with many antiviral agents, monitoring for potential side effects and drug interactions is essential during treatment.
Formula:C9H10FN3O3
InChI:InChI=1S/C9H10FN3O3/c10-6-3-13(9(15)12-8(6)11)7-2-1-5(4-14)16-7/h1-3,5,7,14H,4H2,(H2,11,12,15)/t5-,7+/m1/s1
InChI key:InChIKey=HSBKFSPNDWWPSL-VDTYLAMSSA-N
SMILES:O=C1N([C@H]2O[C@@H](CO)C=C2)C=C(F)C(N)=N1
Synonyms:
  • 2(1H)-Pyrimidinone, 4-amino-1-[(2S,5R)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-fluoro-
  • 2(1H)-Pyrimidinone, 4-amino-1-[2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-fluoro-, (2S-cis)-
  • 4-Amino-1-[(2S,5R)-2,5-dihydro-5-(hydroxymethyl)-2-furanyl]-5-fluoro-2(1H)-pyrimidinone
  • 4-amino-5-fluoro-1-[(2S,5R)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]pyrimidin-2(1H)-one
  • <span class="text-smallcaps">L</span>-Fd 4C
  • Ach 126443
  • Beta-<span class="text-smallcaps">L</span>-Fd4C
  • Elvucitabine
  • L-Fd 4C
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