CAS 1818-71-9

2-HYDROXYADENOSINE

Description:

2-Hydroxyadenosine is a purine nucleoside that consists of an adenine base attached to a ribose sugar with a hydroxyl group at the 2-position of the ribose. This modification distinguishes it from adenosine, which lacks the hydroxyl group. The molecular formula of 2-hydroxyadenosine is C10H13N5O4, and it has a molecular weight that reflects its composition of carbon, hydrogen, nitrogen, and oxygen. This compound is known to play a role in various biochemical processes, including cellular signaling and metabolism. It can act as a substrate for certain enzymes and is involved in the regulation of cellular functions. Additionally, 2-hydroxyadenosine has been studied for its potential therapeutic applications, particularly in the context of neuroprotection and anti-inflammatory effects. Its solubility in water and stability under physiological conditions make it a relevant compound in biochemical research. As with many nucleosides, it can be phosphorylated to form nucleotide derivatives, which are crucial for various biological activities.

Formula: C₁₀H₁₃N₅O₅

InChI: InChI=1/C10H13N5O5/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)

InChI key: InChIKey=MIKUYHXYGGJMLM-UUOKFMHZSA-N

SMILES: NC=1C2=C(N(C=N2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)NC(=O)N1

Synonyms:

• 1,2-Dihydro-2-Oxo-Adenosin
• 1,2-Dihydro-2-Oxoadenosine
• 2,3-Dihydro-2-oxoadenosine
• 2,3-dihydro-2-oxo-Adenosine
• 2-Oxoadenosine
• 6-Amino-9-Beta-D-Ribofuranosyl-9H-Purin-2-O
• 6-Amino-9[(1′-<span class="text-smallcaps">D</span>-2′-ribofuranosyl)-4-hydroxy-5-(hydroxymethyl)-oxolan-2-yl]-1H-purin-2-one
• 6-amino-9-pentofuranosyl-1,9-dihydro-2H-purin-2-one
• 9-β-<span class="text-smallcaps">D</span>-Ribofuranosylisoguanine
• 9H-Purin-2-ol, 6-amino-9-Β-<span class="text-smallcaps">D</span>-ribofuranosyl-
• Adenosine, 1,2-dihydro-2-oxo-
• Adenosine, 2,3-dihydro-2-oxo-
• Crotonosid
• Crotonoside
• Isoguanine riboside
• Isoguanineriboside
• Isoguanosine
• NSC 12161
• 9H-Purin-2-ol, 6-amino-9-Β-D-ribofuranosyl-
• Crotonoside >=95% (HPLC)
• 6-amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one
• 9-(b-D-Ribofuranosyl)isoguanine
• 2-?Hydroxyadenosine
• DISCONTINUED. Please see I819500
• ISOGUANOSINE RIBOSIDE
• 9-(β-D-Ribofuranosyl)isoguanine
• 2-HYDROXYADENOSINE
• ISOGUANOSINE(P)
• Adenosine Impurity 6
• 2(1H)-Oxoadenosine
• Regadenoson Impurity 17
• 2-Hydroxydenosine
• iso-Gr
• 6-Amino-9-β-D-ribofuranosyl-9H-purin-2(1H)-one

Adenosine, 2,3-dihydro-2-oxo-

CAS: 1818-71-9

Formula: C₁₀H₁₃N₅O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 283.2407

Ref: IN-DA002349

Crotonoside

CAS: 1818-71-9

Crotonoside

Purity: ≥98%

Molecular weight: 283.24g/mol

Ref: 54-BUP15485

9-(b-D-Ribofuranosyl)isoguanine

CAS: 1818-71-9

Formula: C₁₀H₁₃N₅O₅

Purity: ≥ 98%

Color and Shape: White to off-white powder

Molecular weight: 283.24

Ref: 7W-GN0615

Crotonoside

CAS: 1818-71-9

2-Hydroxyadenosine (crotonoside) and 2-aminoadenosine are 2-Halogenated derivatives of adenosine, are potent depressors, and they are slightly less potent than adenosine.

Formula: C₁₀H₁₃N₅O₅

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 283.244

Ref: BP-BP0408

Crotonoside

CAS: 1818-71-9

Crotonoside (Isoguanosine) is a natural product, which inhibits FLT3 and HDAC3/6 and has research potential for the treatment of acute myeloid leukaemia (AML).

Formula: C₁₀H₁₃N₅O₅

Purity: 98% - >99.99%

Color and Shape: Solid

Molecular weight: 283.24

Ref: TM-T6S0033

Isoguanosine

CAS: 1818-71-9

Isoguanosine

Formula: C₁₀H₁₃N₅O₅

Purity: 95%

Color and Shape: white to off-white crystals

Molecular weight: 283.24g/mol

Ref: 54-BIMN2014

Regadenoson Impurity 17

CAS: 1818-71-9

Formula: C₁₀H₁₃N₅O₅

Molecular weight: 283.24

Ref: 4Z-R-095018

9-(b-D-Ribofuranosyl)isoguanine

CAS: 1818-71-9

9-(B-D-Ribofuranosyl)isoguanine is a purine analogue that is an anti-cancer drug. It has low potency and its biological properties are unknown. It has been shown to be an inhibitor of the polymerase chain reaction in vitro, but it is unclear if this activity will translate to in vivo models. 9-(B-D-Ribofuranosyl)isoguanine is structurally similar to pyrazole, which also inhibits the polymerase chain reaction in vitro. A recent study found that 9-(B-D-Ribofuranosyl)isoguanine may act as a toll-like receptor agonist and suppress lipopolysaccharide (LPS)-induced inflammation in mice, which suggests that this drug may have anti-inflammatory properties.

Formula: C₁₀H₁₃N₅O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 283.25 g/mol

Ref: 3D-NR09651

2-Hydroxyadenosine

CAS: 1818-71-9

Formula: C₁₀H₁₃N₅O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 283.244

Ref: 10-F239124

Regadenoson Impurity 9

CAS: 1818-71-9

Formula: C₁₀H₁₃N₅O₅

Molecular weight: 283.24

Ref: ST-EA-CP-R55011