CAS 181816-48-8: Ombrabulin

Description: Ombrabulin, with the CAS number 181816-48-8, is a synthetic compound that has been investigated for its potential as an anti-cancer agent. It functions primarily as a vascular disrupting agent, targeting the blood vessels that supply tumors, thereby inhibiting their growth and promoting tumor cell death. Ombrabulin is characterized by its ability to disrupt the formation of new blood vessels (angiogenesis) and induce apoptosis in cancer cells. The compound has been studied in various preclinical and clinical settings, particularly in relation to solid tumors. Its mechanism of action involves interference with the microtubule dynamics, which are crucial for cell division and the structural integrity of cells. While promising in early studies, the clinical efficacy and safety profile of Ombrabulin continue to be evaluated through ongoing research. As with many investigational drugs, understanding its pharmacokinetics, potential side effects, and interactions with other therapies is essential for its development in cancer treatment.

Formula: C₂₁H₂₆N₂O₆

InChI: InChI=1S/C21H26N2O6/c1-26-17-8-7-13(9-16(17)23-21(25)15(22)12-24)5-6-14-10-18(27-2)20(29-4)19(11-14)28-3/h5-11,15,24H,12,22H2,1-4H3,(H,23,25)/b6-5-/t15-/m0/s1

InChI key: InChIKey=IXWNTLSTOZFSCM-YVACAVLKSA-N

SMILES: O=C(NC1=CC(=CC=C1OC)C=CC2=CC(OC)=C(OC)C(OC)=C2)C(N)CO

Synonyms:

• (2S)-2-Amino-3-hydroxy-N-[2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]propanamide
• Propanamide, 2-amino-3-hydroxy-N-[2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]-, (2S)-
• Propanamide, 2-amino-3-hydroxy-N-[2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]-, [S-(Z)]-
• Ombrabulin

Ombrabulin

CAS: 181816-48-8

Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through …

• Formula: C₂₁H₂₆N₂O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 402.44

Propanamide, 2-amino-3-hydroxy-N-[2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]-, (2S)-

CAS: 181816-48-8

• Formula: C₂₁H₂₆N₂O₆
• Purity: 98.00%
• Color and Shape: Solid
• Molecular weight: 402.4409

Ombrabulin

CAS: 181816-48-8

• Formula: C₂₁H₂₆N₂O₆
• Color and Shape: Neat
• Molecular weight: 402.441

Ombrabulin

CAS: 181816-48-8

Ombrabulin is a potential anticancer agent that inhibits the formation of new blood vessels in …

• Formula: C₂₁H₂₆N₂O₆
• Purity: Min. 95%
• Molecular weight: 402.44 g/mol