CAS 1818314-88-3

PD-1/PD-L1-IN1

Description:

PD-1/PD-L1-IN1, with the CAS number 1818314-88-3, is a small molecule inhibitor that targets the programmed cell death protein 1 (PD-1) and its ligand (PD-L1). This compound is primarily studied in the context of cancer immunotherapy, as it plays a crucial role in modulating the immune response against tumors. By inhibiting the PD-1/PD-L1 interaction, PD-1/PD-L1-IN1 can enhance T-cell activation and proliferation, potentially leading to improved anti-tumor immunity. The substance is characterized by its ability to selectively bind to the PD-1 receptor, thereby blocking the inhibitory signals that cancer cells exploit to evade immune detection. Its chemical structure typically includes specific functional groups that facilitate this interaction, although detailed structural information is proprietary. Research into PD-1/PD-L1-IN1 is ongoing, focusing on its efficacy, safety, and potential applications in combination therapies for various malignancies. As with many investigational drugs, further studies are necessary to fully understand its pharmacokinetics, pharmacodynamics, and therapeutic potential.

Formula: C₃₆H₃₃ClN₂O₇

Synonyms:

• BMS-1166 (Synonyms: PD-1/PD-L1-IN1)
• D-Proline, 1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl]-4-hydroxy-, (4R)-
• PD-1/PD-L1-IN1
• BMS-1166 (PD-1/PD-L1-IN1)
• PD-1/PD-L1-IN1 BMS-1166

BMS-1166

CAS: 1818314-88-3

Formula: C₃₆H₃₃ClN₂O₇

Purity: 98%

Color and Shape: Solid

Molecular weight: 641.1094

Ref: IN-DA01FNPO

(2R,4R)-1-(5-Chloro-2-((3-Cyanobenzyl)Oxy)-4-((3-(2,3-Dihydrobenzo[b][1,4]Dioxin-6-Yl)-2-Methylbenzyl)Oxy)Benzyl)-4-Hydroxypyrrolidine-2-Carboxylic Acid

CAS: 1818314-88-3

(2R,4R)-1-(5-Chloro-2-((3-Cyanobenzyl)Oxy)-4-((3-(2,3-Dihydrobenzo[b][1,4]Dioxin-6-Yl)-2-Methylbenzyl)Oxy)Benzyl)-4-Hydroxypyrrolidine-2-Carboxylic Acid

Purity: 99%,99%ee

Molecular weight: 641.11g/mol

Ref: 54-OR1023845

BMS-1166

CAS: 1818314-88-3

BMS-1166

Purity: ≥98%

Molecular weight: 641.11g/mol

Ref: 54-BUP04540

BMS-1166

CAS: 1818314-88-3

BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.

Formula: C₃₆H₃₃ClN₂O₇

Purity: 99.22%

Color and Shape: Solid

Molecular weight: 641.11

Ref: TM-T5697

BMS-1166

CAS: 1818314-88-3

BMS-1166 is a small molecule immunotherapy agent that functions as a PD-1 antagonist. It is derived from targeted drug design, focusing on disrupting the interaction between the programmed cell death protein 1 (PD-1) and its ligands, PD-L1 and PD-L2.

Formula: C₃₆H₃₃ClN₂O₇

Purity: Min. 95%

Molecular weight: 641.11 g/mol

Ref: 3D-TXC31488