
CAS 1818885-28-7
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Found 5 products.
ARV-825
CAS:ARV-825: PROTAC recruits BRD4 to cereblon for rapid BRD4 degradation in all tested BL cells.Formula:C46H47ClN8O9SPurity:97.15% - 98%Color and Shape:SolidMolecular weight:923.43ARV-825
CAS:Controlled ProductARV-825 is a small molecule that inhibits the activity of enzymes in the secretase pathway, which are involved in the production of amyloid beta peptides. It has been shown to inhibit tumor growth in mouse xenografts with a significant cytotoxic effect. ARV-825 causes cell cycle arrest and apoptosis by inhibiting transcription-polymerase chain reaction and DNA synthesis. The molecule also inhibits Jak2 V617F, which is thought to be implicated in Alzheimer's disease. ARV-825 has been shown to significantly inhibit cell proliferation without any cytotoxicity at concentrations up to 100 μM.Formula:C46H47ClN8O9SPurity:Min. 95%Molecular weight:923.43 g/mol



