CAS 181954-34-7

Fmoc-Dap-OH

Description:

Fmoc-Dap-OH, or 9-fluorenylmethoxycarbonyl-2,3-diaminopropanoic acid, is a protected amino acid commonly used in peptide synthesis. The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality, allowing for selective reactions during the synthesis process. This compound features a diamine structure, which includes two amine groups, making it versatile for creating various peptide sequences. Fmoc-Dap-OH is typically utilized in solid-phase peptide synthesis (SPPS), where the Fmoc group can be easily removed under basic conditions, facilitating the sequential addition of amino acids. The presence of the diamine allows for the introduction of unique structural features into peptides, potentially enhancing their biological activity or stability. Additionally, Fmoc-Dap-OH is characterized by its solubility in organic solvents, which is advantageous for its use in synthetic protocols. Overall, this compound is a valuable building block in the field of medicinal chemistry and peptide research.

Formula: C₁₈H₁₈N₂O₄

InChI: InChI=1/C18H18N2O4/c19-9-16(17(21)22)20-18(23)24-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10,19H2,(H,20,23)(H,21,22)/t16-/m0/s1

SMILES: c1ccc2c(c1)c1ccccc1C2COC(=N[C@@H](CN)C(=O)O)O

Synonyms:

• Fmoc-L-2,3-diaminopropionic acid hydrochloride
• Fmoc-Dap
• 3-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine
• Fmoc-L-Dapa-Oh

Fmoc-Dap-OH

CAS: 181954-34-7

Educt for the synthesis of Fmoc-β-azidoalanine, which has been incorporated as an IR-probe into peptides.

Formula: C₁₈H₁₈N₂O₄

Purity: > 99%

Color and Shape: Whitish Powder

Molecular weight: 326.35

Ref: 01-4012066

L-Alanine, 3-amino-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

CAS: 181954-34-7

Formula: C₁₈H₁₈N₂O₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 326.3465

Ref: IN-DA00238U

Fmoc-Dap-OH

CAS: 181954-34-7

Fmoc-Dap-OH

Formula: C₁₈H₁₈N₂O₄

Purity: 98%

Color and Shape: off-white solid

Molecular weight: 326.35g/mol

Ref: 54-OR960676

Fmoc-Dap-OH

CAS: 181954-34-7

Molecular weight: 326.35

Ref: 7W-GM2373

Fmoc-Dap-OH

CAS: 181954-34-7

Formula: C₁₈H₁₈N₂O₄

Purity: 95%

Color and Shape: Off-white crystalline powder

Molecular weight: 326.352

Ref: 10-F236731