CAS 182004-65-5

2-[4-[(4-Nitrophenyl)methoxy]phenyl]ethyl carbamimidothioate methanesulfonate (1:1)

Description:

2-[4-[(4-Nitrophenyl)methoxy]phenyl]ethyl carbamimidothioate methanesulfonate (1:1), with CAS number 182004-65-5, is a chemical compound characterized by its complex structure, which includes a carbamimidothioate functional group and a methanesulfonate salt. This compound features a nitrophenyl moiety, which is known for its electron-withdrawing properties, potentially influencing the compound's reactivity and solubility. The presence of the methoxy group enhances its lipophilicity, which may affect its biological activity and interaction with various biological targets. The methanesulfonate component contributes to the overall solubility in polar solvents, making it suitable for various applications in medicinal chemistry and research. Additionally, the compound may exhibit specific pharmacological properties due to its unique structural features, which could be explored in drug development or as a biochemical probe. As with many chemical substances, safety and handling precautions should be observed, given the potential toxicity associated with nitro groups and other reactive functionalities.

Formula: C₁₆H₁₇N₃O₃S·CH₄O₃S

InChI: InChI=1S/C16H17N3O3S.CH4O3S/c17-16(18)23-10-9-12-3-7-15(8-4-12)22-11-13-1-5-14(6-2-13)19(20)21;1-5(2,3)4/h1-8H,9-11H2,(H3,17,18);1H3,(H,2,3,4)

InChI key: InChIKey=WGIKEBHIKKWJLG-UHFFFAOYSA-N

SMILES: C(OC1=CC=C(CCSC(=N)N)C=C1)C2=CC=C(N(=O)=O)C=C2.S(C)(=O)(=O)O

Synonyms:

• 2-(2-(4-(4-Nitrobenzyloxy)Phenyl)Ethyl)Isothiourea, Methane Sulfonate
• 2-[4-[(4-Nitrophenyl)methoxy]phenyl]ethyl carbamimidothioate methanesulfonate (1:1)
• 2-{4-[(4-Nitrobenzyl)Oxy]Phenyl}Ethyl Carbamimidothioate Methanesulfonate (1:1)
• Carbamimidothioic acid, 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester, methanesulfonate (1:1)
• Carbamimidothioic acid, 2-[4-[(4-nitrophenyl)methoxy]phenyl]ethyl ester, monomethanesulfonate
• Kb-R 7943
• Kb-R7943
• Kb-R7943 Mesylate
• KB-R 7943 mesylate

CARBAMIMIDOTHIOIC ACID, 2-[4-[(4-NITROPHENYL)METHOXY]PHENYL]ETHYL ESTER, METHANESULFONATE (1:1)

CAS: 182004-65-5

Formula: C₁₇H₂₁N₃O₆S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 427.4951

Ref: IN-DA00239H

S-[4-[(4-Nitrobenzyl)Oxy]Phenethyl]Isothiourea Methanesulfonate

CAS: 182004-65-5

S-[4-[(4-Nitrobenzyl)Oxy]Phenethyl]Isothiourea Methanesulfonate

Purity: 99%

Molecular weight: 427.49g/mol

Ref: 54-OR1014898

KB-R7943 mesylate

CAS: 182004-65-5

KB-R7943 mesylate

Purity: ≥95%

Molecular weight: 427.5g/mol

Ref: 54-BUP13258

KB-R7943 mesylate

CAS: 182004-65-5

KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.

Formula: C₁₇H₂₁N₃O₆S₂

Purity: 99.88% - ≥95%

Color and Shape: Solid

Molecular weight: 427.5

Ref: TM-T6144

KB-R 7943

CAS: 182004-65-5

Formula: C₁₆H₁₇N₃O₃S·CH₄O₃S

Purity: >98.0%(HPLC)

Color and Shape: White to Yellow to Green powder to crystal

Molecular weight: 427.49

Ref: 3B-N0966

KB-R7943 Mesylate

Controlled Product

CAS: 182004-65-5

Applications KB-R7943 Mesylate is a selective inhibitor of the reverse mode of Na+/Ca2+ exchange in cells expressing NCX1.
References Iwamoto, T. et al.: J. Biol. Chem., 271, 22391 (1996)

Formula: C₁₆H₁₇N₃O₃S·(CH₄O₃S)

Color and Shape: Neat

Molecular weight: 427.5

Ref: TR-K475400

KB-R7943

CAS: 182004-65-5

KB-R7943 is a polymerase chain inhibitor that has been shown to be effective in the treatment of atrial fibrillation. It inhibits the activity of DNA polymerase, which is required for replication and transcription of DNA. KB-R7943 also has been shown to increase intracellular calcium levels and inhibit mitochondrial membrane potential, leading to cardioprotective effects. KB-R7943 has inhibitory properties on the ryanodine receptor and exchangers, which are involved in cardiac excitation–contraction coupling. KB-R7943 also has been shown to reduce myocardial infarction size and improve heart function following an injury.

Formula: C₁₇H₂₁N₃O₆S₂

Purity: Min. 95%

Molecular weight: 427.49 g/mol

Ref: 3D-HHA00465

KB-R7943

CAS: 182004-65-5

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 427.489990234375

Ref: 10-F047228