CAS 1820565-69-2

PIM447 2HCl

CAS: 1820565-69-2

Formula: C₂₄H₂₃F₃N₄O·2HCl

Molecular weight: 440.47 2*36.46

Ref: 4Z-P-225002

PIM-447 dihydrochloride

CAS: 1820565-69-2

PIM-447 dihydrochloride is a potent small molecule kinase inhibitor, which is synthesized as a selective inhibitor of PIM kinases. These kinases, part of the serine/threonine kinase family, are implicated in various cellular processes, including cell cycle progression and survival, making them a target of interest in oncology research. PIM-447 acts by binding to the ATP-binding pocket of PIM kinases, thereby inhibiting their activity and disrupting downstream signaling pathways that promote tumor growth and survival.

Formula: C₂₄H₂₅Cl₂F₃N₄O

Purity: Min. 95%

Molecular weight: 513.38 g/mol

Ref: 3D-VXC56569

PIM-447 dihydrochloride

CAS: 1820565-69-2

PIM-447 dihydrochloride is an orally available and selective inhibitor of pan-PIM kinase(Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively).

Formula: C₂₄H₂₅Cl₂F₃N₄O

Purity: 98%

Color and Shape: Solid

Molecular weight: 513.38

Ref: TM-T12473