CAS 1820708-73-3

SKA-121

CAS: 1820708-73-3

SKA-121 is a selective KCa3.1 activator (EC50s: 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively).

Formula: C₁₂H₁₀N₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 198.22

Ref: TM-T16891

SKA-121

CAS: 1820708-73-3

SKA-121 is a synthetic antimicrobial peptide, which is derived from a combinatorial library of synthetic peptides. The source of SKA-121 involves bioengineering techniques to mimic naturally occurring antimicrobial peptides, enhancing their stability and efficacy. Its mode of action involves disrupting bacterial cell membranes, leading to cell lysis and death. This disruption is primarily due to the peptide's amphipathic nature, allowing it to integrate into lipid bilayers, destabilizing the membrane structure. SKA-121 is utilized in various applications including antibacterial coatings, infection control, and as a research tool to study microbial resistance mechanisms. Its versatile application extends to medical devices, surfaces, and potential therapeutic options where bacterial infection poses substantial challenges. The efficacy of SKA-121 against multidrug-resistant strains underlines its importance as a research focus for developing next-generation antimicrobials.

Formula: C₁₂H₁₀N₂O

Purity: Min. 95%

Molecular weight: 198.22 g/mol

Ref: 3D-VXC70873