CAS 18210-71-4

(3aS,3′aR,3′′aR,8aS,8′aR,8′′aR)-2,2′,2′′,3,3′,3′′,8,8′,8′′,8a,8′a,8′′a-Dodecahydro-1,1′,1′′-trimethyl-3a,3′a(1H,1′H):7′,3′′a(1′′H)-terpyrrolo[2,3-b]indole

Description:

The chemical substance known as (3aS,3′aR,3′′aR,8aS,8′aR,8′′aR)-2,2′,2′′,3,3′,3′′,8,8′,8′′,8a,8′a,8′′a-Dodecahydro-1,1′,1′′-trimethyl-3a,3′a(1H,1′H):7′,3′′a(1′′H)-terpyrrolo[2,3-b]indole, with CAS number 18210-71-4, is a complex organic compound characterized by its intricate polycyclic structure. This substance features multiple fused rings, including a terpyrrolo framework, which contributes to its unique chemical properties. The presence of multiple stereocenters indicates that the compound can exist in various stereoisomeric forms, potentially influencing its biological activity and interactions. The trimethyl groups and dodecahydro structure suggest a degree of saturation, which may affect its solubility and reactivity. Such compounds are often of interest in medicinal chemistry due to their potential pharmacological properties, including effects on biological systems. Understanding the specific characteristics of this compound, including its molecular geometry and functional groups, is essential for exploring its applications in research and industry.

Formula: C₃₃H₃₈N₆

InChI: InChI=1S/C33H38N6/c1-37-18-15-31(21-9-4-6-13-25(21)34-28(31)37)23-11-8-12-24-27(23)36-30-33(24,17-20-39(30)3)32-16-19-38(2)29(32)35-26-14-7-5-10-22(26)32/h4-14,28-30,34-36H,15-20H2,1-3H3/t28-,29+,30-,31-,32-,33+/m1/s1

InChI key: InChIKey=DPVWJPVYOXKFRQ-BDMNMGLZSA-N

SMILES: CN1[C@@]2([C@@](C=3C(N2)=C(C=CC3)[C@@]45C=6C(N[C@@]4(N(C)CC5)[H])=CC=CC6)(CC1)[C@]78C=9C(N[C@]7(N(C)CC8)[H])=CC=CC9)[H]

Synonyms:

• 3a,3′a(1H,1′H):7′,3′′a(1′′H)-Terpyrrolo[2,3-b]indole, 2,2′,2′′,3,3′,3′′,8,8′,8′′,8a,8′a,8′′a-dodecahydro-1,1′,1′′-trimethyl-, stereoisomer
• Hodgkinsine
• (3aS,3′aR,3′′aR,8aS,8′aR,8′′aR)-2,2′,2′′,3,3′,3′′,8,8′,8′′,8a,8′a,8′′a-Dodecahydro-1,1′,1′′-trimethyl-3a,3′a(1H,1′H):7′,3′′a(1′′H)-terpyrrolo[2,3-b]indole
• Stereoisomer of 2,2′,2′′,3,3′,3′′,8,8′,8′′,8a,8′a,8′′a-dodecahydro-1,1′,1′′-trimethyl-3a,3′a(1H,1′H):7′,3′′a(1′′H)-terpyrrolo[2,3-b]indole
• 3a,3′a(1H,1′H):7′,3′′a(1′′H)-Terpyrrolo[2,3-b]indole, 2,2′,2′′,3,3′,3′′,8,8′,8′′,8a,8′a,8′′a-dodecahydro-1,1′,1′′-trimethyl-, (3aS,3′aR,3′′aR,8aS,8′aR,8′′aR)-

Hodgkinsine

CAS: 18210-71-4

Hodgkinsine, a pyrrolidinoindoline alkaloid with analgesic properties, found in P. colorata, increases pain tolerance in mice at 5 mg/kg.

Formula: C₃₃H₃₈N₆

Color and Shape: Solid

Molecular weight: 518.70

Ref: TM-T38209

Hodgkinsine

CAS: 18210-71-4

Hodgkinsine is a trimeric indolizidine alkaloid, which is a natural compound sourced from the plant genus Psychotria, commonly found in tropical regions. This compound is characterized by its complex chemical structure and biological activity derived from its plant origin. The mode of action of Hodgkinsine involves modulating neurotransmitter systems, particularly by interacting with monoamine transporters and receptors. This interaction leads to its notable analgesic and potential psychoactive properties.

Formula: C₃₃H₃₈N₆

Purity: Min. 95%

Molecular weight: 518.70 g/mol

Ref: 3D-TAA21071