CAS 1821498-25-2

Amlodipine Impurity 18

CAS: 1821498-25-2

Formula: C₁₇H₁₉ClN₂O₅

Molecular weight: 366.80

Ref: 4Z-A-0845

3-O-Desethyl-5-O-desmethyl amlodipine

CAS: 1821498-25-2

3-O-Desethyl-5-O-desmethyl amlodipine is a drug product that can be used as an analytical reference standard. It is metabolized in vivo to form 5-O-desmethyl amlodipine, which is the active form of this drug. 3-O-Desethyl-5-O-desmethyl amlodipine is also an impurity in the drug product Amlodipine besylate and its CAS number is 1821498-25-2. The synthetic route for this compound starts with the reaction of 2,3,4,6 trichlorobenzeneethanol with sodium hydroxide followed by hydrogenation of the intermediate to yield 3-(2,6 dichlorophenyl) propanoic acid. This acid was then reacted with methylamine to yield 3-(2,6 dichlorophenyl)-N-[(methylamino) methyl]propionamide.

Formula: C₁₇H₁₉ClN₂O₅

Purity: Min. 95%

Molecular weight: 366.8 g/mol

Ref: 3D-ID153421

Amlodipine Diacid

CAS: 1821498-25-2

Formula: C₁₇H₁₉ClN₂O₅

Molecular weight: 366.80

Ref: ST-EA-CP-A5017