CAS 1821666-71-0

Pazopanib Impurity 17

CAS: 1821666-71-0

Formula: C₁₄H₁₆N₆

Molecular weight: 268.32

Ref: ST-EA-CP-P58017

N4-​(2,​3-​Dimethyl-​2H-​indazol-​6-​yl)​-​N4-​methyl-2,​4-​pyrimidinediamine

Controlled Product

CAS: 1821666-71-0

Applications N4-​(2,​3-​Dimethyl-​2H-​indazol-​6-​yl)​-​N4-​methyl-2,​4-​pyrimidinediamine is a degredation product of Pazopanib (P210925), an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
References Olaussen, K., et al.: Oncogen., 28, 4249 (2009), Sleijfer, S., et al.: J. Clin. Oncol., 27, 3126 (2009), Chan, A., et al.: Drugs, 69, 167 (2009), Patel, P. et al.: J. Mass. Spec., 50, 918 (2015);

Formula: C₁₄H₁₆N₆

Color and Shape: Neat

Molecular weight: 268.32

Ref: TR-D447263