CAS 1823122-52-6

DOTA-NHS-ester Hexafluorophosphate TFA Salt (Technical Grade)

Description:

DOTA-NHS-ester Hexafluorophosphate TFA Salt is a chemical compound commonly used in bioconjugation and radiopharmaceutical applications. It is characterized by the presence of a DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) moiety, which is a chelating agent that can form stable complexes with metal ions, making it valuable in imaging and therapeutic applications. The NHS (N-hydroxysuccinimide) ester functionality allows for efficient coupling to amine-containing biomolecules, facilitating the formation of stable conjugates. The hexafluorophosphate counterion contributes to the compound's solubility and stability in various solvents. As a TFA (trifluoroacetic acid) salt, it is typically used in a technical grade, indicating it may contain impurities and is suitable for research and development rather than pharmaceutical use. Overall, this compound is significant in the fields of medicinal chemistry and molecular imaging, providing a versatile tool for the development of targeted therapies and diagnostic agents.

Formula: C₂₂H₃₃F₉N₅O₁₂P

Synonyms:

• DOTA-NHS-ester Hexafluorophosphate TFA Salt (Technical Grade)
• DOTA-NHS-ester Hexafluorophosphate TFA Salt

DOTA-NHS Hexafluorophosphate Trifluoroacetate

CAS: 1823122-52-6

Formula: C₂₀H₃₁N₅O₁₀·xC₂HF₃O₂·HF₆P

Purity: >95.0%(T)

Color and Shape: White to Light yellow powder to crystal

Ref: 3B-D6007

Gadobutrol Impurity 86 Hexafluorophosphate TFA Salt (Technical Grade)

CAS: 1823122-52-6

Formula: C₂₀H₃₁N₅O₁₀·F₆HP·C₂HF₃O₂

Molecular weight: 501.49 145.97 114.02

Ref: 4Z-G-31110

DOTA-NHS-ester Hexafluorophosphate TFA Salt (Technical Grade)

CAS: 1823122-52-6

Stability Hygroscopic
Applications DOTA-NHS-ester Hexafluorophosphate TFA Salt is used as a reagent in the preparation of metal or radiometal-labeled-urea- and carbamate-based PSMA inhibitors for PSMA-targeted imaging and radiotherapy.
References Ray, S., et al.: PCT Int. Appl. (2015), WO 2015171792 A1 20151112

Formula: C₂₀H₃₁N₅O₁₀·C₂HF₃O₂·HPF₆

Color and Shape: Neat

Molecular weight: 501.49 + 114.02 + 145.97

Ref: TR-D494867

DOTA-NHS ester compound with hexafluorophosphate, 2,2,2-trifluoroacetate

CAS: 1823122-52-6

DOTA-NHS ester compound with hexafluorophosphate, 2,2,2-trifluoroacetate is a fine chemical that is used as a building block in the synthesis of complex compounds. It can be used to synthesize useful scaffolds and reaction intermediates in organic synthesis and biochemistry research. This compound is also an excellent reagent for the formation of esters and phosphoesters. The CAS number for this product is 1823122-52-6.

Formula: C₂₀H₃₁N₅O₁₀·C₂HF₃O₂·HPF₆

Purity: (Hplc-Ms) Min. 90 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 761.48 g/mol

Ref: 3D-FD168133

DOTA-NHS-ester Hexafluorophosphate TFA Salt

CAS: 1823122-52-6

Formula: C₂₀H₃₂N₅O₁₀F₆HPC₂HF₃O₂

Molecular weight: 501.49 : 145.97 : 114.02

Ref: ST-EA-CP-G39013