CAS 1824-52-8

bemetizide

Description:

Bemetizide is a chemical compound classified as a diuretic, primarily used in the treatment of hypertension and edema associated with various medical conditions. It belongs to the class of thiazide-like diuretics, which function by inhibiting sodium reabsorption in the kidneys, leading to increased urine output and reduced blood volume. The molecular structure of bemetizide includes a sulfonamide group, which is characteristic of many diuretics, contributing to its pharmacological activity. It is typically administered orally and is known for its effectiveness in managing fluid retention and lowering blood pressure. Bemetizide may also exhibit side effects, including electrolyte imbalances, dehydration, and potential allergic reactions, necessitating careful monitoring during treatment. As with any medication, its use should be guided by a healthcare professional, considering individual patient factors and potential interactions with other drugs. Overall, bemetizide serves as an important therapeutic agent in the management of cardiovascular and renal conditions.

Formula: C₁₅H₁₆ClN₃O₄S₂

InChI: InChI=1/C15H16ClN3O4S2/c1-9(10-5-3-2-4-6-10)15-18-12-7-11(16)13(24(17,20)21)8-14(12)25(22,23)19-15/h2-9,15,18-19H,1H3,(H2,17,20,21)

InChI key: InChIKey=PYVUMAGVCSQCBD-UHFFFAOYSA-N

SMILES: O=S1(=O)C=2C(NC(C(C)C3=CC=CC=C3)N1)=CC(Cl)=C(S(N)(=O)=O)C2

Synonyms:

• 2H-1,2,4-Benzothiadiazine, 3,4-dihydro-6-chloro-3-(alpha-methylbenzyl)-7-sulfamoyl-, 1,1-dioxide
• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(1-phenylethyl)-, 1,1-dioxide
• 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-(α-methylbenzyl)-, 1,1-dioxide
• 6-Chlor-3,4-dihydro-3-(alpha-methylbenzyl)-7-sulfamoyl-2H-1,2,4-benzothiadiazine-1,1-dioxide
• 6-Chloro-3,4-dihydro-3-(alpha-methylbenzyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-chloro-3-(1-phenylethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• Bemeticide
• Bemetizida
• Bemetizida [INN-Spanish]
• Bemetizide [INN:BAN]
• Bemetizidum
• Bemetizidum [INN-Latin]
• Brn 0631888
• Dehydrosanol
• Diu 60
• Pertensosanol
• Su 7078
• Unii-Ezn4D2O31B
• Bemetizide
• Bemetizide
• Bemetizide (10mM in DMSO)
• 6-Chloro-3,4-dihydro-3-(a-methylbenzyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-Chloro-3,4-dihydro-3-(α-methylbenzyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

Bemetizide

CAS: 1824-52-8

Formula: C₁₅H₁₆ClN₃O₄S₂

Molecular weight: 401.88

Ref: 4Z-B-294001

Bemetizide

CAS: 1824-52-8

Formula: C₁₅H₁₆ClN₃O₄S₂

Color and Shape: Neat

Molecular weight: 401.89

Ref: TR-B131510

Bemetizide (1 mg/ml in DMSO)

CAS: 1824-52-8

Formula: C₁₅H₁₆ClN₃O₄S₂

Color and Shape: Single Solution

Molecular weight: 401.89

Ref: TR-KIT9935

6-Chloro-3,4-dihydro-3-(a-methylbenzyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

CAS: 1824-52-8

6-Chloro-3,4-dihydro-3-(a-methylbenzyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide is an active metabolite of the drug benzbromarone. It is primarily administered as a diuretic to treat high blood pressure and congestive heart failure. The pharmacodynamics of this drug are related to its ability to inhibit the activity of sodium channels in vascular smooth muscle cells and thereby reduce the force of contraction and relax the vessel wall. 6CBDMTD has shown an increase in glomerular filtration rate in patients with congestive heart failure. This drug also decreases the plasma concentration of fatty acids by inhibiting the formation of lipoprotein particles. 6CBDMTD has been shown to be effective at lowering diastolic and systolic blood pressure levels in patients with hypertension.

Formula: C₁₅H₁₆ClN₃O₄S₂

Purity: Min. 95%

Molecular weight: 401.89 g/mol

Ref: 3D-FC145398