CAS 182495-81-4

Cytidine, N-benzoyl-2′-deoxy-2′-fluoro-5-methyl-

Description:

Cytidine, N-benzoyl-2′-deoxy-2′-fluoro-5-methyl- is a modified nucleoside that features a benzoyl group attached to the cytidine structure, along with a deoxy sugar and a fluorine atom at the 2' position. This compound is characterized by its unique structural modifications, which can influence its biological activity and stability. The presence of the fluorine atom may enhance the resistance of the nucleoside to enzymatic degradation, making it of interest in pharmaceutical research, particularly in the development of antiviral or anticancer agents. The benzoyl group can also affect the compound's solubility and interaction with biological targets. As a nucleoside analog, it may mimic natural nucleosides in biological systems, potentially interfering with nucleic acid synthesis or function. Overall, this compound represents a valuable tool in medicinal chemistry and molecular biology, with applications in drug design and therapeutic development.

Formula: C₁₇H₁₈FN₃O₅

InChI: InChI=1S/C17H18FN3O5/c1-9-7-21(16-12(18)13(23)11(8-22)26-16)17(25)20-14(9)19-15(24)10-5-3-2-4-6-10/h2-7,11-13,16,22-23H,8H2,1H3,(H,19,20,24,25)/t11-,12-,13-,16-/m1/s1

InChI key: InChIKey=MQFJFDMISFYWRE-BRXULGCHSA-N

SMILES: F[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)N=C(NC(=O)C3=CC=CC=C3)C(C)=C2

Synonyms:

• Cytidine, N-benzoyl-2′-deoxy-2′-fluoro-5-methyl-
• 594: PN: WO03048315 PAGE: 147-201 claimed sequence

2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine

CAS: 182495-81-4

2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-Modified pyrimidine nucleoside, 2'-Modified nucleoside

Formula: C₁₇H₁₈FN₃O₅

Color and Shape: Solid

Molecular weight: 363.34

Ref: TM-TNU0950

2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine

CAS: 182495-81-4

2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine is a monophosphate nucleoside that is used as an antiviral and anticancer drug. It inhibits the synthesis of DNA, RNA, and proteins by acting as a chain terminator. 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine inhibits viral replication by blocking the formation of viral DNA. This compound is also used for the treatment of cancerous cells. 2'-Deoxy-2'-fluoro-N4-benzoyl-5-methylcytidine has shown to be effective against leukemia cells in culture.
2'-Deoxy -2' -fluoro N4 benzoyl 5 methyl cytidine has been synthesized with high purity and is available in a variety of modifications including phosphoramidites and deoxyribonucleosides.

Purity: Min. 95%

Ref: 3D-ND144505