CAS 182507-22-8: RALOXIFENE-4-GLUCURONIDE

Description:Raloxifene-4-glucuronide is a metabolite of raloxifene, a selective estrogen receptor modulator (SERM) primarily used in the treatment and prevention of osteoporosis in postmenopausal women. This compound is characterized by its glucuronidation, a process that enhances the solubility and excretion of drugs. Raloxifene-4-glucuronide exhibits a high affinity for estrogen receptors, though its activity may differ from that of its parent compound. It is typically found in biological fluids following the administration of raloxifene, serving as a marker for the drug's metabolic pathway. The compound is soluble in water due to its glucuronide moiety, which contributes to its pharmacokinetic properties. Its role in pharmacology includes potential implications in modulating bone density and reducing the risk of breast cancer, similar to raloxifene. Understanding the characteristics of raloxifene-4-glucuronide is essential for evaluating the efficacy and safety of raloxifene therapy, as well as for monitoring its metabolic profile in clinical settings.

Formula:C₃₄H₃₅NO₁₀S

InChI:InChI=1S/C34H35NO10S/c36-21-8-13-24-25(18-21)46-32(20-6-11-23(12-7-20)44-34-30(40)28(38)29(39)31(45-34)33(41)42)26(24)27(37)19-4-9-22(10-5-19)43-17-16-35-14-2-1-3-15-35/h4-13,18,28-31,34,36,38-40H,1-3,14-17H2,(H,41,42)/t28-,29-,30+,31-,34+/m0/s1

InChI key:InChIKey=VHXYPEXOSLGZKH-WKRHDJAJSA-N

SMILES:O=C(O)C1OC(OC=2C=CC(=CC2)C=3SC4=CC(O)=CC=C4C3C(=O)C5=CC=C(OCCN6CCCCC6)C=C5)C(O)C(O)C1O

Synonyms:
(4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy-D4]benzoyl]benzo[b]thien-2-yl]phenyl-D-glucopyranosiduronic acid)
4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy-d4]benzoyl]benzo[b]thien-2-yl]phenyl-b-D-glucopyranosiduronic Acid
4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-D-glucopyranosiduronicacid
4-[6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl-b-D-glucopyranosiduronic Acid
Raloxifene-D4-4'-Glucuronide
β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 4-[6-hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl

Found 12 products.

Product data	Purity	Price range	Estimated delivery
β-D-Glucopyranosiduronic acid, 4-[6-hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]benzoyl]benzo[b]thien-2-yl]phenyl REF: IN-DA0023Y6CAS: 182507-22-8	- - -	To inquire	Thu 27 Mar 25
Raloxifene-4'-Glucuronide REF: 4Z-R-012CAS: 182507-22-8	- - -	To inquire	Fri 28 Mar 25
Raloxifene-4'-Glucuronide Lithium Salt REF: 4Z-R-017CAS: 182507-22-8	- - -	To inquire	Fri 28 Mar 25
Raloxifene 4'-glucuronide REF: TM-T12686CAS: 182507-22-8	98%	To inquire	Fri 28 Mar 25
Raloxifene 4'-O-?-D-glucuronide REF: 54-BICL2515CAS: 182507-22-8	- - -	696.00 €~1,101.00 €	Thu 03 Apr 25
Raloxifene-4''-D-glucuronide lithium salt REF: 7W-GC8389CAS: 182507-22-8	- - -	618.00 €~2,828.00 €	Thu 03 Apr 25
Raloxifene-d4 4’-Glucuronide REF: TR-R100022CAS: 182507-22-8	- - -	470.00 €~3,192.00 €	Tue 08 Apr 25
Raloxifene 4’-Glucuronide REF: TR-R100020CAS: 182507-22-8	- - -	419.00 €~2,799.00 €	Tue 08 Apr 25
Raloxifene 4'-D-glucuronide REF: 3D-MR07277CAS: 182507-22-8	Min. 95%	139.00 €~1,071.00 €	Mon 07 Apr 25
Raloxifene-4'-D-glucuronide lithium salt REF: 3D-MR09926CAS: 182507-22-8	Min. 95%	To inquire	Mon 07 Apr 25
Raloxifene 4’-β-D-Glucuronide Lithium Salt REF: TR-R100021CAS: 182507-22-8	- - -	343.00 €~2,213.00 €	Wed 07 May 25
Raloxifene-d4 4’-β-D-Glucuronide Lithium Salt REF: TR-R100023CAS: 182507-22-8	- - -	1,547.00 €	Wed 07 May 25