CAS 1825345-33-2

AZ9482

Description:

AZ9482, identified by its CAS number 1825345-33-2, is a chemical compound that belongs to a class of substances known for their potential applications in various fields, including medicinal chemistry and material science. While specific characteristics such as molecular weight, boiling point, and solubility may vary, compounds like AZ9482 are typically characterized by their unique structural features, which can influence their reactivity and interaction with biological systems. AZ9482 may exhibit properties such as moderate to high stability under standard conditions, and its solubility can vary depending on the solvent used. Additionally, compounds in this category may demonstrate biological activity, making them of interest for drug development or as research tools. Safety data sheets and material safety data should be consulted for handling and toxicity information, as these compounds can have specific hazards associated with them. Overall, AZ9482 represents a notable example of modern synthetic chemistry with potential implications in various scientific domains.

Formula: C₂₆H₂₂N₆O₂

Synonyms:

• AZ 9482;AZ-9482
• AZ9482

2-(4-(3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)nicotinonitrile

CAS: 1825345-33-2

Formula: C₂₆H₂₂N₆O₂

Purity: 98%

Molecular weight: 450.4919

Ref: IN-DA01KL6A

2-(4-(3-((4-Oxo-3,4-Dihydrophthalazin-1-Yl)Methyl)Benzoyl)Piperazin-1-Yl)Nicotinonitrile

CAS: 1825345-33-2

2-(4-(3-((4-Oxo-3,4-Dihydrophthalazin-1-Yl)Methyl)Benzoyl)Piperazin-1-Yl)Nicotinonitrile

Purity: 98%

Molecular weight: 450.49g/mol

Ref: 54-OR1022906

AZ9482

CAS: 1825345-33-2

AZ9482

Purity: ≥98%

Molecular weight: 450.49g/mol

Ref: 54-BUP03709

AZ9482

CAS: 1825345-33-2

AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.

Formula: C₂₆H₂₂N₆O₂

Purity: 99.18% - 99.86%

Color and Shape: Solid

Molecular weight: 450.49

Ref: TM-T22264

AZ9482

CAS: 1825345-33-2

Ref: 7W-GW4253

AZ9482

CAS: 1825345-33-2

AZ9482 is a small molecule that binds to the acceptor site of the enzyme DNA polymerase β. It has potent antitumor effects, and shows high selectivity for tumor cells over normal cells. AZ9482 inhibits the growth of tumor cells in low nanomolar concentrations. This compound has been shown to inhibit the synthesis of DNA, RNA and proteins in cancer cells, which may be due to its ability to bind to the polymerase acceptor site. AZ9482 has been shown to have anti-inflammatory properties by inhibiting nuclear factor-kappaB (NF-κB) activation.

Formula: C₂₆H₂₂N₆O₂

Purity: Min. 95%

Molecular weight: 450.5 g/mol

Ref: 3D-AYC34533