CAS 1828-12-2

1-Propanone, 1-(4-fluorophenyl)-3-(1-piperidinyl)-, hydrochloride (1:1)

Description:

1-Propanone, 1-(4-fluorophenyl)-3-(1-piperidinyl)-, hydrochloride (1:1), commonly known as a piperidine derivative, is a chemical compound characterized by its structural features that include a propanone backbone, a 4-fluorophenyl group, and a piperidine moiety. This compound typically appears as a white to off-white crystalline solid and is soluble in water and various organic solvents, which is indicative of its polar functional groups. The presence of the piperidine ring contributes to its potential biological activity, often associated with central nervous system effects. The hydrochloride salt form enhances its stability and solubility, making it suitable for pharmaceutical applications. As with many compounds containing fluorine, the 4-fluorophenyl group may influence the compound's lipophilicity and receptor binding properties. Safety data should be consulted for handling and exposure risks, as compounds of this nature may exhibit pharmacological effects and require careful management in laboratory and clinical settings.

Formula: C₁₄H₁₈FNO·ClH

InChI: InChI=1S/C14H18FNO.ClH/c15-13-6-4-12(5-7-13)14(17)8-11-16-9-2-1-3-10-16;/h4-7H,1-3,8-11H2;1H

InChI key: InChIKey=IOEPRJMKWRLAHK-UHFFFAOYSA-N

SMILES: C(CCN1CCCCC1)(=O)C2=CC=C(F)C=C2.Cl

Synonyms:

• 1-(4-Fluorophenyl)-3-(1-piperidinyl)-1-propanone hydrochloride
• 1-(4-Fluorophenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride
• 1-Propanone, 1- (4-fluorophenyl)-3-(1-piperidinyl)-, hydrochloride
• 1-Propanone, 1-(4-Fluorophenyl)-3-(1-Piperidinyl)-, Hydrochloride (1:1)
• 1-Propanone, 1-(4-fluorophenyl)-3-(1-piperidinyl)-, hydrochloride (9CI)
• 4′-Fluoro-3-piperidinopropiophenone hydrochloride
• Propiophenone, 4′-fluoro-3-piperidino-, hydrochloride
• β-(N-Piperidyl)-p-fluoropropiophenone hydrochloride
• 1-(4-Fluorophenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride (1:1)

1-(4-Fluorophenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride

CAS: 1828-12-2

1-(4-Fluorophenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride is a pyridinium compound that has been shown to have an antiarrhythmic effect. It inhibits the activity of the potassium channel and calcium ion channels, which are responsible for stabilizing the heart rate. 1-(4-Fluorophenyl)-3-(piperidin-1-yl)propan-1-one hydrochloride also modulates anion channels and can be used to treat hyperactivity. The diprotonated form of this drug is active against anions. The carbonyl group in this compound is capable of forming hydrogen bonds with other molecules. This structural feature is responsible for the drug's pharmacological effect and its ability to bind to proteins, including enzymes such as pyrrole reductase.

Formula: C₁₄H₁₉ClFNO

Purity: Min. 95%

Molecular weight: 271.76 g/mol

Ref: 3D-BAA82812