CAS 182924-36-3

Pyridine, 5-(bromomethyl)-2-chloro-

Description:

Pyridine, 5-(bromomethyl)-2-chloro- is a heterocyclic organic compound characterized by a pyridine ring, which is a six-membered aromatic ring containing one nitrogen atom. This compound features a bromomethyl group and a chloro substituent at specific positions on the pyridine ring, contributing to its reactivity and potential applications in organic synthesis. The presence of the bromomethyl group makes it a useful intermediate for further chemical transformations, such as nucleophilic substitutions or coupling reactions. The chlorine atom can also participate in various reactions, enhancing the compound's versatility in synthetic chemistry. Pyridine derivatives are often employed in pharmaceuticals, agrochemicals, and as building blocks in the synthesis of more complex molecules. The compound's physical properties, such as solubility and boiling point, are influenced by the substituents and the nitrogen atom in the ring, which can affect its polarity and interaction with other substances. Safety data should be consulted for handling and storage, as halogenated compounds can pose health and environmental risks.

Formula: C₆H₅BrClN

InChI: InChI=1/C6H5BrClN/c7-3-5-1-2-6(8)9-4-5/h1-2,4H,3H2

SMILES: c1cc(Cl)ncc1CBr

Synonyms:

• 5-(Bromomethyl)-2-Chloropyridine

Pyridine, 5-(bromomethyl)-2-chloro-

CAS: 182924-36-3

Formula: C₆H₅BrClN

Purity: 98%

Color and Shape: Solid

Molecular weight: 206.4676

Ref: IN-DA002497

5-(Bromomethyl)-2-Chloropyridine

CAS: 182924-36-3

5-(Bromomethyl)-2-Chloropyridine

Purity: 98%

Molecular weight: 206.47g/mol

Ref: 54-OR1011721

5-(Bromomethyl)-2-chloropyridine

CAS: 182924-36-3

5-(Bromomethyl)-2-chloropyridine is a drug with mediated activity. It is a potent inhibitor of the enzyme aldehyde oxidase, which is responsible for the oxidation of aldehydes to carboxylic acids. The inhibition of this enzyme leads to an increase in the concentration of reactive aldehydes and reactive oxygen species, which can lead to cell death. 5-(Bromomethyl)-2-chloropyridine has been shown to be effective as an anti-inflammatory agent in animal models and has also been used as an immunosuppressant in organ transplantation.
5-(Bromomethyl)-2-chloropyridine analogues have been synthesized and shown to be potent inhibitors of aldehyde oxidase, with much better pharmacokinetics than the parent molecule.

Formula: C₆H₅BrClN

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 206.47 g/mol

Ref: 3D-FB147805

5-(Bromomethyl)-2-chloropyridine

CAS: 182924-36-3

Formula: C₆H₅BrClN

Purity: 95%

Color and Shape: Solid

Molecular weight: 206.47

Ref: 10-F077227

5-Bromomethyl-2-chloropyridine

Controlled Product

CAS: 182924-36-3

Applications 5-Bromomethyl-2-chloropyridine is a reagent used in the preparation of gonadotropin-releasing hormone receptor antagonist using uracil scaffold.
References Kim, S., et al.: J. Med. Chem., 59, 9150 (2016)

Formula: C₆H₁₃NO₃

Color and Shape: Neat

Molecular weight: 147.172

Ref: TR-B697130