CAS 18303-04-3: N-(tert-butoxycarbonyl)-P-toluene-sulfonamide
CAS 18303-04-3: N-(tert-butoxycarbonyl)-P-toluene-sulfonamide
Description:N-(tert-butoxycarbonyl)-P-toluene-sulfonamide, commonly referred to as Boc-P-toluene-sulfonamide, is a chemical compound characterized by its sulfonamide functional group and a tert-butoxycarbonyl (Boc) protecting group. This compound typically appears as a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethyl sulfoxide, but has limited solubility in water. The Boc group serves as a protective moiety for amines, facilitating various synthetic applications, particularly in peptide synthesis and organic chemistry. The presence of the toluene sulfonamide moiety enhances its utility in medicinal chemistry, as sulfonamides are known for their antibacterial properties. The compound is often used in the preparation of more complex molecules, acting as an intermediate in the synthesis of pharmaceuticals and biologically active compounds. Safety data indicates that, like many sulfonamides, it should be handled with care, as it may cause irritation upon contact with skin or eyes. Proper laboratory safety protocols should be followed when working with this substance.
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