CPP9, with the CAS number 1831064-63-1, is a chemical compound that has garnered interest in various fields, particularly in medicinal chemistry. It is characterized by its specific molecular structure, which includes functional groups that contribute to its biological activity. CPP9 is known for its role as a peptide or peptide-like molecule, often studied for its potential therapeutic applications, including antiviral properties. The compound may exhibit specific interactions with biological targets, influencing cellular processes. Its solubility, stability, and reactivity are important characteristics that determine its efficacy in biological systems. Additionally, CPP9's synthesis and characterization involve standard organic chemistry techniques, ensuring purity and confirming its identity through methods such as NMR and mass spectrometry. As research continues, the understanding of CPP9's mechanisms of action and potential applications in drug development may expand, highlighting its significance in the field of chemistry and pharmacology.

CPP9

1831064-63-1: CPP9, with the CAS number 1831064-63-1, is a chemical compound that has garnered interest in various fields, particularly in medicinal chemistry. It is characterized by its specific molecular structure, which includes functional groups that contribute to its biological activity. CPP9 is known for its role as a peptide or peptide-like molecule, often studied for its potential therapeutic applications, including antiviral properties. The compound may exhibit specific interactions with biological targets, influencing cellular processes. Its solubility, stability, and reactivity are important characteristics that determine its efficacy in biological systems. Additionally, CPP9's synthesis and characterization involve standard organic chemistry techniques, ensuring purity and confirming its identity through methods such as NMR and mass spectrometry. As research continues, the understanding of CPP9's mechanisms of action and potential applications in drug development may expand, highlighting its significance in the field of chemistry and pharmacology.

<p>CPP9 is a small, amphipathic, cyclic peptide which is a highly efficient cell penetrating peptide (CPP). CPP9 binds directly to the plasma membrane phospholipids and enters mammalian cells via endocytosis. CPP9 is then efficiently released from the endosome. CPP9 is capable of delivering a variety of cargo molecules (such as small-molecule dyes, peptides, and proteins) into the cytosol of mammalian cells with efficiencies 4- to 12-fold higher than that of R9, Tat, and penetratin. This high cytosolic delivery efficiency is due to a vastly improved endosomal escape process.  CPP9 exits the endosome by binding to the endosomal membrane and inducing CPP-enriched lipid domains to bud off as small vesicles. Together with the high proteolytic stability of cyclic CPP9, its low cytotoxicity, and oral bioavailability, CPP9 may provide a powerful system for intracellular delivery of therapeutic agents and chemical probes.</p>

CAS 1831064-63-1

CPP9

CPP9

Ref: 3D-CRB1001385