CAS 183198-48-3

N-Methyl Iso Desloratadine

Description:

N-Methyl Iso Desloratadine, with the CAS number 183198-48-3, is a derivative of desloratadine, which is an antihistamine commonly used to treat allergic symptoms. This compound is characterized by its selective antagonistic activity at peripheral H1 histamine receptors, which helps alleviate symptoms such as sneezing, runny nose, and itching associated with allergies. N-Methyl Iso Desloratadine is known for its improved pharmacokinetic properties, including enhanced bioavailability and a longer duration of action compared to its parent compound. It is typically administered orally and is well-tolerated, with a lower incidence of sedation compared to first-generation antihistamines. The chemical structure includes a methyl group substitution, which contributes to its unique properties. As with many antihistamines, it may also exhibit some anticholinergic effects, although these are generally mild. Overall, N-Methyl Iso Desloratadine represents a significant advancement in the development of non-sedating antihistamines, providing effective relief from allergic symptoms with minimal side effects.

Formula: C₂₀H₂₁ClN₂

Synonyms:

• N-Methyl Iso Desloratadine
• N-Methyl Iso Desloratadine 1
• Desloratadine Impurity 39
• Desloratadine impurity 26
• 8-Chloro-6,11-dihydro-11-(1,2,3,6-tetrahydro-1-Methyl-4-pyridinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

Loratadine Impurity 38

CAS: 183198-48-3

Formula: C₂₀H₂₁ClN₂

Molecular weight: 324.85

Ref: 4Z-L-10105

N-Methyl Iso Desloratadine

Controlled Product

CAS: 183198-48-3

Applications Loratadine (L469575) impurity. Used for preparation of tricyclic amides and ureas useful for inhibition of G-protein function and for treatment of proliferative diseases.
References Billah., et al.: Lipids, 26, 1172 (1991), Piwinski., et al.: J. Med. Chem., 34, 457 (1991),

Formula: C₂₀H₂₁ClN₂

Color and Shape: Neat

Molecular weight: 324.847

Ref: TR-M314300