CAS 183200-12-6

Guanylin (human)

Description:

Guanylin is a peptide hormone that plays a crucial role in regulating electrolyte and water balance in the human body. It is primarily produced in the intestines and acts on the guanylate cyclase receptor, leading to an increase in intracellular cyclic guanosine monophosphate (cGMP) levels. This signaling pathway promotes the secretion of electrolytes and water into the intestinal lumen, which can help in the regulation of fluid homeostasis and blood pressure. Guanylin is involved in various physiological processes, including the modulation of gastrointestinal motility and the promotion of sodium excretion by the kidneys. Its dysregulation has been implicated in conditions such as diarrhea and hypertension. The CAS number 183200-12-6 specifically identifies this peptide, which is characterized by its unique amino acid sequence and structure. As a member of the natriuretic peptide family, guanylin shares functional similarities with other peptides that influence cardiovascular and renal functions, highlighting its importance in maintaining overall physiological balance.

Formula: C₅₈H₈₇N₁₅O₂₁S₄

Synonyms:

• H-Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-Oh
• H-Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-Oh(Disulfide Bridge: 4-12 And 7-15)
• Pgtceicayaactgc (Disulfide Bridge: 4-12 And 7-15)
• Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys
• H-Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH(Cys4-Cys12, Cys7-Cys15)
• H-Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys-OH (Disulfide bonds between Cys4 and Cys12/Cys7 and Cys15)

Guanylin (human)

CAS: 183200-12-6

Endogenous intestinal guanylate cyclase activator.

Formula: C₅₈H₈₇N₁₅O₂₁S₄

Purity: > 97%

Color and Shape: White Powder

Molecular weight: 1458.68

Ref: 01-4030693

Guanylin(human)

CAS: 183200-12-6

Peptide that activates gut guanylyl cyclase, secreted by GI mucosa, regulates water and electrolytes in gut and kidneys.

Formula: C₅₈H₈₇N₁₅O₂₁S₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 1458.65

Ref: TM-TP2034

Guanylin (Human)

CAS: 183200-12-6

Guanylin is a human gastrointestinal hormone which can be used to activate the transmembrane receptor Guanylate Cyclase C on the intestinal epithelial cells surface. This product contains disulfide bonds between Cys4-Cys12 and Cys7-Cys15 and is available as a 0.1mg vial.

Formula: C₅₈H₈₇N₁₅O₂₁S₄

Purity: Min. 95%

Molecular weight: 1,458.7 g/mol

Ref: 3D-PGN-4274-S

Guanylin (human)

CAS: 183200-12-6

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Formula: C₅₈H₈₇N₁₅O₂₁S₄

Purity: Min. 95%

Molecular weight: 1,458.66 g/mol

Ref: 3D-FG108840