CAS 183321-62-2

4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-dimethoxy-

Description:

4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-dimethoxy- is a chemical compound characterized by its quinazoline core structure, which is a bicyclic compound containing a benzene ring fused to a pyrimidine ring. This specific derivative features a dimethoxy substitution at the 6 and 7 positions, enhancing its solubility and potentially influencing its biological activity. The presence of an ethynylphenyl group at the N-position introduces a degree of rigidity and may affect the compound's interaction with biological targets. The compound is likely to exhibit properties typical of quinazolinamine derivatives, such as potential pharmacological activity, including anti-cancer or anti-inflammatory effects, although specific biological activities would depend on further empirical studies. Its molecular structure suggests it may participate in hydrogen bonding and π-π stacking interactions, which are relevant in drug design and molecular recognition. As with many organic compounds, its stability, reactivity, and solubility will be influenced by the functional groups present and the overall molecular conformation.

Formula: C₁₈H₁₅N₃O₂

Synonyms:

• 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-dimethoxy-

BML-265

CAS: 183321-62-2

BML-265 is a potent inhibitor of EGFR tyrosine kinase (EGFR tyrosine kinase). It disrupts Golgi apparatus integrity in human cells and hinders the transport of secretory proteins across various substances. In contrast, BML-265 does not affect the integrity and transport of the Golgi apparatus in rodent cells.

Formula: C₁₈H₁₅N₃O₂

Color and Shape: Solid

Molecular weight: 305.331

Ref: TM-T204769