CAS: 183321-74-6 - Erlotinib

Formula: C₂₂H₂₃N₃O₄

InChI: InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)

InChI key: InChIKey=AAKJLRGGTJKAMG-UHFFFAOYSA-N

SMILES: C#CC1=CC=CC(=C1)NC=2N=CN=C3C=C(OCCOC)C(OCCOC)=CC32

Synonyms:

• 4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-
• 4-[(3-Ethynylphenyl)Amino]-6,7-Bis(2-Methoxyethoxy)Quinazoline
• Erlotinib & its intermediates (Developing)
• Erlotinib Base
• Erlotinin
• N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine
• N-(3-Ethynylphenyl)[6,7-Bis(2-Methoxyethoxy)Quinazolin-4-Yl]Amine
• NSC 718781
• Osi 744
• R 1415

4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-

CAS: 183321-74-6

• Formula: C₂₂H₂₃N₃O₄
• Purity: ≥98%
• Color and Shape: Solid
• Molecular weight: 393.4357

Erlotinib

CAS: 183321-74-6

Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment …

• Formula: C₂₂H₂₃N₃O₄
• Purity: 99.98%
• Color and Shape: White To Off-White Powder
• Molecular weight: 393.44

Erlotinib

CAS: 183321-74-6

• Formula: C₂₂H₂₃N₃O₄
• Purity: ≥ 99.0% (anhydrous basis)
• Color and Shape: White to light-yellow powder
• Molecular weight: 393.44

Erlotinib Free Base

CAS: 183321-74-6

• Formula: C₂₂H₂₃N₃O₄
• Purity: By hplc: >99% (Typical Value in Batch COA)
• Color and Shape: white solid
• Molecular weight: 393.44g/mol

N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine

CAS: 183321-74-6

Applications Erlotinib is a EGFR-targeted drug in the treatment of non-small cell lung cancer. EGFR …

• Formula: C₂₂H₂₃N₃O₄
• Color and Shape: White to Off-White Solid
• Molecular weight: 393.44

Erlotinib base

CAS: 183321-74-6

Tyrosine kinase inhibitor; affects EGFR receptor; pancreatic cancer treatment

• Formula: C₂₂H₂₃N₃O₄
• Purity: Min. 99 Area-%
• Color and Shape: Powder
• Molecular weight: 393.44 g/mol