CAS 183387-50-0

17α-Ethynyl-5α-androstane-3α,17β-diol

Description:

17α-Ethynyl-5α-androstane-3α,17β-diol, identified by its CAS number 183387-50-0, is a synthetic steroid compound that exhibits characteristics typical of anabolic steroids. It is structurally related to testosterone, featuring an ethynyl group at the 17α position, which enhances its oral bioavailability and metabolic stability. This compound is primarily studied for its potential applications in hormone replacement therapy and anabolic effects in muscle growth. Its chemical structure includes a steroid backbone with specific functional groups that contribute to its biological activity. The compound may interact with androgen receptors, influencing various physiological processes such as protein synthesis and muscle hypertrophy. Additionally, it may exhibit varying degrees of androgenic and anabolic properties, which are critical in evaluating its therapeutic potential and safety profile. As with many synthetic steroids, the use of this compound is subject to regulatory scrutiny due to potential side effects and implications for athletic performance enhancement.

Formula: C₂₁H₃₂O₂

InChI: InChI=1S/C21H32O2/c1-4-21(23)12-9-18-16-6-5-14-13-15(22)7-10-19(14,2)17(16)8-11-20(18,21)3/h1,14-18,22-23H,5-13H2,2-3H3/t14-,15+,16+,17-,18-,19-,20-,21-/m0/s1

InChI key: InChIKey=CKAXZOYFIHQCBN-JRRMKBMNSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@]2(C#C)O)[H]

Synonyms:

• 17α-Ethynyl-5α-androstane-3α,17β-diol
• (3α,5α,17α)-Pregn-20-yne-3,17-diol
• HE 3235
• Pregn-20-yne-3,17-diol, (3α,5α,17α)-
• Apoptone
• HE3235
• (3R,5S,8R,9S,10S,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-diol

Apoptone

Controlled Product

CAS: 183387-50-0

Apoptone is a drug that belongs to the group of mitochondrial inhibitors. Apoptone has been shown to be effective in the treatment of cancer, including as an adjunct therapy with chemotherapy drugs. It has also been shown to be effective in treating prostate cancer and damaged skin tissue. Apoptone works by inhibiting mitochondrial enzymes that are involved in the synthesis of ATP, thereby causing cell death. Apoptone is thought to target cancer cells by modulating their metabolism and growth.

Formula: C₂₁H₃₂O₂

Purity: Min. 95%

Molecular weight: 316.5 g/mol

Ref: 3D-IHA38750

HE-3235

CAS: 183387-50-0

Apoptone, a synthetic 3β-androstanediol analogue, is an oral anticancer drug effective against prostate and breast cancer in rodents.

Formula: C₂₁H₃₂O₂

Color and Shape: Solid

Molecular weight: 316.48

Ref: TM-T21886