CAS 1835705-61-7

<span class="text-smallcaps">L</smallcap>-Prolinamide, N-[6-[[5-[(6-chlorohexyl)oxy]pentyl]oxy]-1-oxohexyl]-3-methyl-<smallcap>L</span>-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-

Description:

L-Prolinamide, N-[6-[[5-[(6-chlorohexyl)oxy]pentyl]oxy]-1-oxohexyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)- is a complex organic compound characterized by its intricate molecular structure, which includes multiple functional groups such as amides, hydroxyls, and thiazoles. This compound is likely to exhibit properties typical of amides, including moderate solubility in polar solvents and potential for hydrogen bonding due to the presence of hydroxyl groups. The presence of a thiazole ring may impart unique biological activity, making it of interest in pharmaceutical research. Its chlorohexyl and pentyl ether components suggest potential lipophilicity, which could influence its interaction with biological membranes. The stereochemistry indicated by the (4R) designation suggests specific spatial arrangements that may be crucial for its biological activity. Overall, this compound's characteristics make it a candidate for further investigation in medicinal chemistry and related fields.

Formula: C₃₉H₆₁ClN₄O₆S

InChI: InChI=1S/C39H61ClN4O6S/c1-29-35(51-28-42-29)31-18-16-30(17-19-31)26-41-37(47)33-25-32(45)27-44(33)38(48)36(39(2,3)4)43-34(46)15-9-7-12-22-50-24-14-8-13-23-49-21-11-6-5-10-20-40/h16-19,28,32-33,36,45H,5-15,20-27H2,1-4H3,(H,41,47)(H,43,46)/t32-,33+,36-/m1/s1

InChI key: InChIKey=DVLICOWBWULAJJ-RWTOGVPBSA-N

SMILES: C([C@@H](NC(CCCCCOCCCCCOCCCCCCCl)=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1

Synonyms:

• L-Prolinamide, N-[6-[[5-[(6-chlorohexyl)oxy]pentyl]oxy]-1-oxohexyl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
• (S,R,S)-AHPC-C6-PEG1-C3-PEG1-butyl chloride
• (S,R,S)-AHPC-6-5-6-Cl
• VHL Ligand-Linker Conjugates 11
• (S,R,S)-AHPC-(C3-PEG)2-C6-C
• E3 ligase Ligand-Linker Conjugates 11

E3 Ligase Ligand-Linker Conjugates 11

CAS: 1835705-61-7

Formula: C₃₉H₆₁ClN₄O₆S

Purity: 98%

Molecular weight: 749.4428

Ref: IN-DA01EO9U

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

CAS: 1835705-61-7

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

Purity: 98%

Molecular weight: 749.44g/mol

Ref: 54-OR1032161

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

CAS: 1835705-61-7

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a HaloPROTAC, degrades GFP-HaloTag7 in cells, has VHL ligand & 2-unit PEG.

Formula: C₃₉H₆₁ClN₄O₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 749.44

Ref: TM-T17912

(S,R,S)-AHPC-(C3-​PEG)​2-​C6-​Cl

CAS: 1835705-61-7

Purity: 98%

Molecular weight: 749.45

Ref: 10-F987741

(S,R,S)-AHPC-C6-PEG1-C3-PEG1-butyl chloride

CAS: 1835705-61-7

(S,R,S)-AHPC-C6-PEG1-C3-PEG1-butyl chloride is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. (S,R,S)-AHPC-C6-PEG1-C3-PEG1-butyl chloride is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.

Formula: C₃₉H₆₁ClN₄O₆S

Purity: Min. 95%

Molecular weight: 749.44 g/mol

Ref: 3D-KYC70561