Acid-PEG3-PFP ester, identified by its CAS number 1835759-67-5, is a chemical compound that features a polyethylene glycol (PEG) moiety linked to a perfluorophenyl (PFP) ester group. This compound typically exhibits characteristics such as high solubility in polar solvents due to the PEG segment, which enhances its biocompatibility and hydrophilicity. The PFP group contributes to its reactivity, particularly in coupling reactions, making it useful in bioconjugation and drug delivery applications. The presence of the acid functional group allows for further modifications, enabling the attachment of various biomolecules or therapeutic agents. Additionally, the structure of Acid-PEG3-PFP ester provides a balance between hydrophilic and hydrophobic properties, which can be advantageous in formulating stable emulsions or nanoparticles. Overall, this compound is valuable in the fields of medicinal chemistry and materials science, particularly for applications involving targeted delivery and controlled release of therapeutics.

Acid-PEG3-PFP ester is a PEG linker containing a carboxylic acid and PFP ester end group. The carboxylic acid can react with amines in the presence of activators such as EDC and HATU to form a stable amide bond. The PFP ester can also react with amine groups. The hydrophilic PEG chains increase the water solubility of the compound in aqueous media.

Acid-PEG3-PFP ester

1835759-67-5: Acid-PEG3-PFP ester, identified by its CAS number 1835759-67-5, is a chemical compound that features a polyethylene glycol (PEG) moiety linked to a perfluorophenyl (PFP) ester group. This compound typically exhibits characteristics such as high solubility in polar solvents due to the PEG segment, which enhances its biocompatibility and hydrophilicity. The PFP group contributes to its reactivity, particularly in coupling reactions, making it useful in bioconjugation and drug delivery applications. The presence of the acid functional group allows for further modifications, enabling the attachment of various biomolecules or therapeutic agents. Additionally, the structure of Acid-PEG3-PFP ester provides a balance between hydrophilic and hydrophobic properties, which can be advantageous in formulating stable emulsions or nanoparticles. Overall, this compound is valuable in the fields of medicinal chemistry and materials science, particularly for applications involving targeted delivery and controlled release of therapeutics.

<p>Acid-PEG3-PFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

<p>Acid-PEG3-pfp ester is a PEG compound with two different functional groups (also known as heterobifunctional). Unlike homobifunctional PEG compounds (same functional group on both ends), this type of compounds are more versatile as have two different anchor points. Acid-PEG3-pfp ester is used as a linker and spacer to add a PEG moiety, via pegylation (a bioconjugation technique) to proteins, peptides, oligonucleotides, small molecules and nanoparticles.</p>

CAS 1835759-67-5

Acid-PEG3-PFP ester

Acid-PEG3-PFP ester

Ref: TM-T14103

Acid-PEG3-pfp ester

Ref: 3D-KYC75967