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CAS 18361-47-2

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Leucomycin A7

Description:
Leucomycin A7 is a macrolide antibiotic that is derived from the fermentation of the bacterium *Streptomyces aureofaciens*. It is characterized by its complex structure, which includes a large lactone ring and several sugar moieties, contributing to its biological activity. This compound exhibits antibacterial properties, particularly against Gram-positive bacteria, making it useful in treating various infections. Leucomycin A7 functions by inhibiting bacterial protein synthesis, specifically by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of bacteria. Its pharmacological profile includes a relatively low toxicity to human cells, which is a significant advantage in clinical applications. Additionally, Leucomycin A7 may exhibit some degree of resistance to certain bacterial strains, which is a common challenge in antibiotic therapy. Overall, its unique structure and mechanism of action make Leucomycin A7 an important compound in the field of medicinal chemistry and antibiotic development.
Formula:C38H63NO14
InChI:InChI=1/C38H63NO14/c1-10-28(43)51-36-24(5)49-30(20-38(36,6)46)52-33-23(4)50-37(32(45)31(33)39(7)8)53-34-25(16-17-40)18-21(2)26(41)15-13-11-12-14-22(3)48-29(44)19-27(42)35(34)47-9/h11-13,15,17,21-27,30-37,41-42,45-46H,10,14,16,18-20H2,1-9H3/b12-11+,15-13+/t21-,22-,23-,24+,25-,26+,27-,30+,31-,32-,33-,34+,35+,36+,37+,38-/m1/s1
InChI key:InChIKey=CQSPEFZMAFYKML-RQWHEHCQSA-N
SMILES:O([C@H]1[C@@H](CC=O)C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@@H](C)OC(=O)C[C@@H](O)[C@@H]1OC)[C@H]2[C@H](O)[C@@H](N(C)C)[C@H](O[C@H]3C[C@@](C)(O)[C@@H](OC(CC)=O)[C@H](C)O3)[C@@H](C)O2
Synonyms:
  • (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl]oxy}-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl propanoate (non-preferred name)
  • Turimycin H3
  • (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4R,5S,6S,7S,9R,10R,11E,13E,16R)-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl]oxy}-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl propanoate (non-preferred name)
  • Leucomycin A7
  • Leucomycin V, 4B-propanoate
  • Oxacyclohexadecane, leucomycin V deriv.
  • Leucomycin V 4''-propionate
  • Leucomycin V 4''-propanoate
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Found 2 products.
  • Josamycin EP Impurity I
    Standalix
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    Josamycin EP Impurity I

    CAS:
    Formula:C38H63NO14
    Molecular weight:757.91

    Ref: ST-EA-CP-J1007

    10mg
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    25mg
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    50mg
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    100mg
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  • Leucomycin A7
    Targetmol
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    Leucomycin A7

    CAS:
    <p>Leucomycin A7 is a component of the leucomycin complex, isolated from *Streptomyces kitasatoensis*. It possesses antibacterial activity, effectively inhibiting the growth of gram-positive bacteria, while its inhibitory effect on gram-negative bacteria is comparatively weaker.</p>
    Formula:C38H63NO14
    Color and Shape:Solid
    Molecular weight:757.905

    Ref: TM-TN10662